Direct evidence for tonic sympathetic support of resting metabolic rate in healthy adult humans

MB Monroe, DR Seals, LF Shapiro… - American Journal …, 2001 - journals.physiology.org
The sympathetic nervous system (SNS) plays an important role in the regulation of energy
expenditure. However, whether tonic SNS activity contributes to resting metabolic rate …

Tonic sympathetic support of metabolic rate is attenuated with age, sedentary lifestyle, and female sex in healthy adults

C Bell, DR Seals, MB Monroe, DS Day… - The Journal of …, 2001 - academic.oup.com
We recently demonstrated in young adult humans that the sympathetic nervous system
contributes to the control of resting metabolic rate via tonic β-adrenergic receptor stimulation …

High energy flux mediates the tonically augmented β-adrenergic support of resting metabolic rate in habitually exercising older adults

C Bell, DS Day, PP Jones, DD Christou… - The Journal of …, 2004 - academic.oup.com
The sympathetic nervous system contributes to resting metabolic rate (RMR) via β-
adrenergic receptor (β-AR) stimulation of energy metabolism. RMR and β-AR support of …

Reduced metabolic rate during β-adrenergic blockade in humans

S Welle, RG Schwartz, M Statt - Metabolism, 1991 - Elsevier
We previously reported that 1 week of propranolol treatment (160 to 240 mg/d, orally)
reduced resting metabolic rate (RMR) an average of 9% in healthy men. To determine …

The effect of propranolol on free fatty acid mobilization and resting metabolic rate

L Christin, E Ravussin, C Bogardus, BV Howard - Metabolism, 1989 - Elsevier
The role of the sympathetic nervous system in free fatty acid (FFA) mobilization was
assessed in this study. FFA turnover rate using 1-14 C-palmitic acid and metabolic rate by …

Sympathetic system activity in obesity and metabolic syndrome

N Tentolouris, S Liatis… - Annals of the New York …, 2006 - Wiley Online Library
Obesity is a very common disease worldwide, resulting from a disturbance in the energy
balance. The metabolic syndrome is also a cluster of abnormalities with basic characteristics …

Norepinephrine turnover and energy expenditure in Pima Indian and white men

L Christin, M O'Connell, C Bogardus, E Danforth Jr… - Metabolism, 1993 - Elsevier
There is growing evidence of the involvement of sympathetic nervous system (SNS) activity
in determining metabolic rate. Whole-body plasma norepinephrine turnover and its …

Respiratory quotient is inversely associated with muscle sympathetic nerve activity

S Snitker, PA Tataranni… - The Journal of Clinical …, 1998 - academic.oup.com
The relative amounts of the macronutrients oxidized by an individual are reflected in the
respiratory quotient (RQ), which varies inversely with lipid oxidation. A high RQ, indicating a …

Reduced sympathetic nervous activity. A potential mechanism predisposing to body weight gain.

M Spraul, E Ravussin, AM Fontvieille… - The Journal of …, 1993 - Am Soc Clin Investig
The sympathetic nervous system is recognized to play a role in the etiology of animal and
possibly human obesity through its impact on energy expenditure and/or food intake. We …

Sympathetic neural overdrive in the obese and overweight state: meta-analysis of published studies

G Grassi, A Biffi, G Seravalle, FQ Trevano… - …, 2019 - Am Heart Assoc
Nerve traffic recordings (muscle sympathetic nerve traffic [MSNA]) have shown that
sympathetic activation may occur in obesity. However, the small sample size of the available …