Omega-3 polyunsaturated fatty acids augment the muscle protein anabolic response to hyperinsulinaemia–hyperaminoacidaemia in healthy young and middle-aged …

GI Smith, P Atherton, DN Reeds… - Clinical …, 2011 - portlandpress.com
Increased dietary LC n− 3PUFA (long-chain n− 3 polyunsaturated fatty acid) intake
stimulates muscle protein anabolism in individuals who experience muscle loss due to …

[HTML][HTML] Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial

GI Smith, P Atherton, DN Reeds, BS Mohammed… - The American journal of …, 2011 - Elsevier
Background: Loss of muscle mass with aging is a major public health concern. Omega-3 (n–
3) fatty acids stimulate protein anabolism in animals and might therefore be useful for the …

A randomized trial of the effects of dietary n3-PUFAs on skeletal muscle function and acute exercise response in healthy older adults

HE Kunz, KL Michie, KJ Gries, X Zhang, ZC Ryan… - Nutrients, 2022 - mdpi.com
Skeletal muscle is critical for maintaining mobility, independence, and metabolic health in
older adults. However, a common feature of aging is the progressive loss of skeletal muscle …

Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of …

S Fujita, EL Glynn, KL Timmerman, BB Rasmussen… - Diabetologia, 2009 - Springer
Aims/hypothesis The physiological increase in muscle protein anabolism induced by insulin
is blunted in healthy, glucose-tolerant older adults. We hypothesised that the age-related …

The effect of omega-3 fatty acids on sarcopenia: mechanism of action and potential efficacy

A Therdyothin, N Phiphopthatsanee, M Isanejad - Marine Drugs, 2023 - mdpi.com
Sarcopenia, a progressive disease characterized by a decline in muscle strength, quality,
and mass, affects aging population worldwide, leading to increased morbidity and mortality …

The influence of omega-3 fatty acids on skeletal muscle protein turnover in health, disuse, and disease

C McGlory, PC Calder, EA Nunes - Frontiers in nutrition, 2019 - frontiersin.org
Ingestion of omega-3 fatty acids is known to exert favorable health effects on a number of
biological processes such as improved immune profile, enhanced cognition, and optimized …

Effects of fish oil-derived n-3 polyunsaturated fatty acid on body composition, muscle strength and physical performance in older people: a secondary analysis of a …

D Xu, Y Lu, X Yang, D Pan, Y Wang, S Yin… - Age and …, 2022 - academic.oup.com
Background the effects regarding n-3 polyunsaturated fatty acid (n-3 PUFA)
supplementation on sarcopenia have been explored by several clinical trials. Nonetheless …

[HTML][HTML] Branched-Chain Amino Acids as Fuels and Anabolic Signals in HumanMuscle

MJ Rennie, J Bohe, K Smith, H Wackerhage… - The Journal of …, 2006 - Elsevier
During exercise, there is an increase in amino acid (AA) oxidation accompanied by a
depression in whole-body protein synthesis and an increase in protein breakdown. Leucine …

[HTML][HTML] Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults

AZ Lalia, S Dasari, MM Robinson, H Abid… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
Omega-3 polyunsaturated fatty acids (n3-PUFA) are recognized for their anti-inflammatory
effects and may be beneficial in the context of sarcopenia. We determined the influence of …

Applications of omega-3 polyunsaturated fatty acid supplementation for sport performance

JD Philpott, OC Witard… - Research in sports …, 2019 - Taylor & Francis
ABSTRACT Omega-3 (n-3) polyunsaturated fatty acid (PUFA) supplementation has recently
been proposed as an ergogenic aid for athletes. This claim is primarily based on …