While the incidence of type 1 diabetes continues to rise by 3% each year, the ability to
prevent this disease remains elusive. Hybrid closed loop devices, artificial pancreas …

Abstract Approximately 215,000 people younger than 20 yr of age, or 1 in 500 children and
adolescents, had diabetes in the United States in 2010—and the incidence is rising. We still …

Type 1 diabetes mellitus (T1DM) is the archetypal example of a T cell‐mediated
autoimmune disease characterized by selective destruction of pancreatic β cells. The …

Type 1 diabetes (T1D) is a chronic T-cell mediated autoimmune disease characterized by
destruction of beta cells. Although new data have better defined the complex etiology …

Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by loss of insulin
producing beta cells and reliance on exogenous insulin for survival. T1D is one of the most …

Great strides have been made in our understanding of the natural history of 'pre‐type
1'diabetes as well as in the post diagnosis period. For now, an inability to successfully …

The clinical manifestation of type 1 diabetes mellitus is preceded by an asymptomatic
prodromal period called prediabetes or preclinical diabetes. It may last from a few months to …

General childhood population-based screening for risk of T1D will allow detection of an at-
risk population that can participate in natural history studies to better understand disease …

Type 2 diabetes diagnosed in childhood or early adulthood is termed early-onset type 2
diabetes. Cases of early-onset type 2 diabetes are increasing rapidly globally, alongside …

Much attention has focused on the increasing prevalence of childhood type 2 diabetes
mellitus. However, considerable evidence suggests that the incidence of childhood type 1 …