Diagnostic accuracy, incremental yield and prognostic value of Determine TB-LAM for routine diagnostic testing for tuberculosis in HIV-infected patients requiring …
Background We previously reported that one-third of HIV-positive adults requiring medical
admission to a South African district hospital had laboratory-confirmed tuberculosis (TB) and …
admission to a South African district hospital had laboratory-confirmed tuberculosis (TB) and …
Rapid microbiological screening for tuberculosis in HIV-positive patients on the first day of acute hospital admission by systematic testing of urine samples using Xpert …
SD Lawn, AD Kerkhoff, R Burton, C Schutz, G van Wyk… - BMC medicine, 2015 - Springer
Background Autopsy studies of HIV/AIDS-related hospital deaths in sub-Saharan Africa
reveal frequent failure of pre-mortem diagnosis of tuberculosis (TB), which is found in 34 …
reveal frequent failure of pre-mortem diagnosis of tuberculosis (TB), which is found in 34 …
Rapid urine-based screening for tuberculosis in HIV-positive patients admitted to hospital in Africa (STAMP): a pragmatic, multicentre, parallel-group, double-blind …
A Gupta-Wright, EL Corbett, JJ van Oosterhout… - The Lancet, 2018 - thelancet.com
Background Current diagnostics for HIV-associated tuberculosis are suboptimal, with
missed diagnoses contributing to high hospital mortality and approximately 374 000 annual …
missed diagnoses contributing to high hospital mortality and approximately 374 000 annual …
Diagnostic accuracy of the rapid urine lipoarabinomannan test for pulmonary tuberculosis among HIV-infected adults in Ghana–findings from the DETECT HIV-TB …
S Bjerrum, E Kenu, M Lartey, MJ Newman… - BMC infectious …, 2015 - Springer
Background Rapid diagnostic tests are urgently needed to mitigate HIV-associated
tuberculosis (TB) mortality. We evaluated diagnostic accuracy of the rapid urine …
tuberculosis (TB) mortality. We evaluated diagnostic accuracy of the rapid urine …
The diagnostic accuracy of urine-based Xpert MTB/RIF in HIV-infected hospitalized patients who are smear-negative or sputum scarce
Background Hospitals in sub-Saharan Africa are inundated with HIV-infected patients and
tuberculosis (TB) is the commonest opportunistic infection in this sub-group. Up to one third …
tuberculosis (TB) is the commonest opportunistic infection in this sub-group. Up to one third …
Incremental yield of including determine-TB LAM assay in diagnostic algorithms for hospitalized and ambulatory HIV-positive patients in Kenya
H Huerga, G Ferlazzo, P Bevilacqua, B Kirubi… - PLoS …, 2017 - journals.plos.org
Background Determine-TB LAM assay is a urine point-of-care test useful for TB diagnosis in
HIV-positive patients. We assessed the incremental diagnostic yield of adding LAM to …
HIV-positive patients. We assessed the incremental diagnostic yield of adding LAM to …
Disseminated tuberculosis among hospitalised HIV patients in South Africa: a common condition that can be rapidly diagnosed using urine-based assays
HIV-associated disseminated TB (tuberculosis) has been under-recognised and poorly
characterised. Blood culture is the gold-standard diagnostic test, but is expensive, slow, and …
characterised. Blood culture is the gold-standard diagnostic test, but is expensive, slow, and …
Effect on mortality of point-of-care, urine-based lipoarabinomannan testing to guide tuberculosis treatment initiation in HIV-positive hospital inpatients: a pragmatic …
Background HIV-associated tuberculosis is difficult to diagnose and results in high mortality.
Frequent extra-pulmonary presentation, inability to obtain sputum, and paucibacillary …
Frequent extra-pulmonary presentation, inability to obtain sputum, and paucibacillary …
Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV-associated pulmonary tuberculosis before antiretroviral therapy: a descriptive …
SD Lawn, AD Kerkhoff, M Vogt… - The Lancet infectious …, 2012 - thelancet.com
Background The diagnostic accuracy of sputum smear microscopy and routine chest
radiology for HIV-associated tuberculosis is poor, and culture-based diagnosis is slow …
radiology for HIV-associated tuberculosis is poor, and culture-based diagnosis is slow …
Tuberculosis case finding with combined rapid point-of-care assays (Xpert MTB/RIF and Determine TB LAM) in HIV-positive individuals starting antiretroviral therapy in …
M Floridia, F Ciccacci, M Andreotti… - Clinical Infectious …, 2017 - academic.oup.com
Background Tuberculosis is a major health concern in several countries, and effective
diagnostic algorithms for use in human immunodeficiency virus (HIV)–positive patients are …
diagnostic algorithms for use in human immunodeficiency virus (HIV)–positive patients are …
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