Targeted delivery of hydrogels in human gastrointestinal tract: A review

Z Yang, DJ McClements, C Li, S Sang, L Chen… - Food …, 2023 - Elsevier
The global demand for healthier food products has led to the introduction of functional foods
fortified with bioactive agents, such as vitamins and nutraceuticals. Many of these bioactive …

Therapeutic applications of hydrogels in oral drug delivery

LA Sharpe, AM Daily, SD Horava… - Expert opinion on drug …, 2014 - Taylor & Francis
Introduction: Oral delivery of therapeutics, particularly protein-based pharmaceutics, is of
great interest for safe and controlled drug delivery for patients. Hydrogels offer excellent …

Recent progress in hydrogel delivery systems for improving nutraceutical bioavailability

DJ McClements - Food hydrocolloids, 2017 - Elsevier
Nutraceuticals are bioactive molecules found in foods that may improve human
performance, wellbeing, or health. The potential health benefits of many nutraceuticals are …

Designing hydrogel particles for controlled or targeted release of lipophilic bioactive agents in the gastrointestinal tract

Z Zhang, R Zhang, L Chen, Q Tong… - European Polymer …, 2015 - Elsevier
Numerous lipophilic bioactive agents within the food and pharmaceutical industries need to
be encapsulated within delivery systems to overcome problems associated with poor water …

A novel approach for preparation of pH-sensitive hydrogels for enteric drug delivery

L Dong, AS Hoffman - Journal of Controlled Release, 1991 - Elsevier
A new rationale of preparing pH-sensitive hydrogels based on thermally reversible polymers
is proposed, according to which a new class of hydrogels has been synthesized. These …

[HTML][HTML] Design of a versatile pH-responsive hydrogel for potential oral delivery of gastric-sensitive bioactives

AR Hibbins, P Kumar, YE Choonara, PPD Kondiah… - Polymers, 2017 - mdpi.com
A pH-responsive hydrogel system was prepared by free radical polymerization of acrylamide
and methyl acrylic acid in the presence of NN′-methylene bisacrylamide. Sodium …

[HTML][HTML] Hydrogels: Characteristics and application as delivery systems of phenolic and aroma compounds

I Ćorković, A Pichler, J Šimunović, M Kopjar - Foods, 2021 - mdpi.com
Complex challenges are facing the food industry as it develops novel and innovative
products for the consumer marketplace. Food processing and preservation are primarily …

[HTML][HTML] Binary hydrogels: Induction methods and recent application progress as food matrices for bioactive compounds delivery—A bibliometric review

A Hilal, A Florowska, M Wroniak - Gels, 2023 - mdpi.com
Food hydrogels are biopolymeric materials made from food-grade biopolymers with gelling
properties (proteins and polysaccharides) and a 3D network capable of incorporating large …

[HTML][HTML] A comprehensive review on the utilization of biopolymer hydrogels to encapsulate and protect probiotics in foods

N Nezamdoost-Sani, MA Khaledabad, S Amiri… - International Journal of …, 2024 - Elsevier
Probiotics must survive in foods and passage through the human mouth, stomach, and small
intestine to reach the colon in a viable state and exhibit their beneficial health effects …

pH-responsive, lysine-based hydrogels for the oral delivery of a wide size range of molecules

KA Watkins, R Chen - International Journal of Pharmaceutics, 2015 - Elsevier
Hydrogels synthesized from poly (l-lysine isophthalamide)(PLP) crosslinked with l-lysine
methyl ester were investigated as drug delivery systems for a wide size range of molecules …