Pericytes are skeletal muscle resident, multipotent stem cells that are localized to the
microvasculature. In vivo, studies have shown that they respond to damage through …

Introduction: Skeletal muscle regeneration following damage relies on proliferation and
differentiation of muscle precursor cells (MPCs). We recently observed increased NF‐kB …

By providing a source of α-smooth muscle actin (α-SMA)-expressing myofibroblasts,
microvascular pericytes contribute to the matrix remodeling that occurs during tissue repair …

Fibrotic disease is associated with matrix deposition that results in the loss of organ function.
Pericytes, the precursors of myofibroblasts, are a source of pathological matrix collagens …

Limited data exist on the molecular mechanisms that govern skeletal muscle regeneration in
humans. This study characterized the early molecular alterations in humans to eccentric …

Introduction Fibrosis, or scar formation, is a pathological condition characterized by
excessive production and accumulation of collagen, loss of tissue architecture, and organ …

Background Peripheral arterial disease (PAD) affects millions of people and compromises
quality of life. Critical limb ischemia (CLI), which is the most advanced stage of PAD, can …

Pericytes are perivascular cells that envelop and make intimate connections with adjacent
capillary endothelial cells. Recent studies show that they may have a profound impact in …

Pericytes are periendothelial mesenchymal cells residing within the microvasculature.
Skeletal muscle and cardiac pericytes are now recognized to fulfill an increasing number of …

Pericytes are mural cell that have been found to play important roles in promoting blood
vessel development and regulating blood flow. The signals that attract pericytes to maturing …