Medulloblastoma is an aggressively growing tumour, arising in the cerebellum or
medulla/brain stem. It is the most common malignant brain tumour in children, and shows …

Medulloblastoma is a malignant childhood brain tumour comprising four discrete subgroups.
Here, to identify mutations that drive medulloblastoma, we sequenced the entire genomes of …

Medulloblastoma is a malignant childhood cerebellar tumour type that comprises distinct
molecular subgroups. Whereas genomic characteristics of these subgroups are well …

Medulloblastoma encompasses a collection of clinically and molecularly diverse tumour
subtypes that together comprise the most common malignant childhood brain tumour …

Medulloblastomas are the most common malignant brain tumours in children. Identifying
and understanding the genetic events that drive these tumours is critical for the development …

Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated
with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive …

Current therapies for medulloblastoma, a highly malignant childhood brain tumour, impose
debilitating effects on the developing child, and highlight the need for molecularly targeted …

Medulloblastoma is a highly malignant paediatric brain tumour, often inflicting devastating
consequences on the developing child. Genomic studies have revealed four distinct …

Sonic hedgehog medulloblastoma encompasses a clinically and molecularly diverse group
of cancers of the developing central nervous system. Here, we use unbiased sequencing of …

Childhood brain tumors have suspected prenatal origins. To identify vulnerable
developmental states, we generated a single-cell transcriptome atlas of> 65,000 cells from …