Drug resistance in patients experiencing early virological failure under a triple combination including indinavir

O Gallego, C de Mendoza, MJ Pérez-Elías… - Aids, 2001 - journals.lww.com
Drug resistance in patients experiencing early virological f... : AIDS Drug resistance in patients
experiencing early virological failure under a triple combination including indinavir : AIDS Log …

Clinical implications of genotypic resistance to the newer antiretroviral drugs in HIV-1–infected patients with virological failure

JM Llibre, JM Schapiro, B Clotet - Clinical infectious diseases, 2010 - academic.oup.com
Virological suppression rates achieved with the new antiretroviral drugs in patients with
virological failure and resistance to multiple drug classes are nearly matching the rates seen …

Absence of zidovudine resistance in antiretroviral-naive patients following zidovudine/lamivudine/protease inhibitor combination therapy: virological evaluation of the …

M Maguire, M Gartland, S Moore, A Hill, M Tisdale… - Aids, 2000 - journals.lww.com
Objectives To assess the role of resistance mutations in subjects experiencing virological
failure on zidovudine (ZDV) and lamivudine (3TC) combined with a protease inhibitor (PI) to …

Low prevalence of primary mutations associated with drug resistance in antiviral-naive patients at therapy initiation

CF Perno, A Cozzi-Lepri, C Balotta, A Bertoli, M Violin… - Aids, 2002 - journals.lww.com
Objective To assess the prevalence of mutations in the reverse-transcriptase (RT) and
protease (PR) region in a cohort of chronically-infected HIV-positive patients requiring highly …

Phenotypic changes in drug susceptibility associated with failure of human immunodeficiency virus type 1 (HIV-1) triple combination therapy

NT Parkin, YS Lie, N Hellmann… - The Journal of …, 1999 - academic.oup.com
The emergence of drug-resistant human immunodeficiency virus type 1 is a frequent cause
of failure of combination therapies comprising reverse transcriptase and protease inhibitors …

Drug resistance at low viraemia in HIV-1-infected patients with antiretroviral combination therapy

S Aleman, K Söderbärg, U Visco-Comandini, G Sitbon… - Aids, 2002 - journals.lww.com
Objective To study the appearance of drug-induced mutations at low viraemia in treated HIV-
1-infected patients. Design and methods Fourteen patients, who received their first (n= 5) …

Persistence of earlier HIV‐1 drug resistance mutations at new treatment failure

V Svedhem, A Lindkvist, K Lidman… - Journal of medical …, 2002 - Wiley Online Library
The objective was to study the persistence of drug resistance mutations detected earlier at
virological failure during second or third line antiretroviral therapy. Therefore, in HIV‐1 …

Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies

E Race, E Dam, V Obry, S Paulous, F Clavel - Aids, 1999 - journals.lww.com
Objective: To assess the patterns of HIV phenotypic cross-resistance to protease inhibitors
(PI) in patients experiencing viral load rebound on combination therapy including a PI …

Genotypic and phenotypic resistance patterns in early-stage HIV-1-infected patients failing initial therapy with stavudine, didanosine and nevirapine

C Vidal, M Arnedo, F Garcia, G Mestre… - Antiviral …, 2002 - journals.sagepub.com
The objectives of this study were to determine the genotypic and phenotypic patterns of
resistance in a group of early-stage antiretroviral-naive patients failing initial therapy with …

Indinavir plasma concentrations and resistance mutations in patients experiencing early virological failure

D González de Requena, O Gallego… - AIDS research and …, 2003 - liebertpub.com
Virological failure under protease inhibitor (PI)-based antiretroviral regimens is often not
explained by the selection of resistance mutations. The role of low indinavir (IDV) plasma …