Investigating protein expression, modifications and interactions in the brain: Protocol for preparing rodent brain tissue for mass spectrometry-based quantitative-and …

L Dwomoh - Methods in Cell Biology, 2021 - Elsevier
Neurodegenerative diseases remain a major global health challenge, affecting millions of
individuals worldwide. Despite significant research efforts, the etiology and pathological …

Proteomic Analyses of the Mouse Brain

J Li - Cerebral Cortex Development: Methods and Protocols, 2024 - Springer
Proteomics is a scientific field that aims to identify and characterize all proteins within a
biological system, including their posttranslational modifications (PTMs), quantitative …

Proteomics in the Neurosciences

MO Collins, H Husi, SGN Grant - Proteomics: Biomedical and …, 2004 - Springer
The field of proteomics aims to provide a comprehensive view of the characteristics and
function of every protein present within a given biological system. The genome, which …

A primer on concepts and applications of proteomics in neuroscience

F Hosp, M Mann - Neuron, 2017 - cell.com
The enormous complexity of the central nervous system has impeded its systemic
exploration for decades but powerful" omic" technologies are now pushing forward the …

Defining the Cellular Interactome of Disease-Linked Proteins in Neurodegeneration

V Arndt, I Vorberg - Protein Interactions, 2012 - books.google.com
Age-related neurodegenerative diseases are recognized as a major health issue worldwide.
Due to our aging society, the number of people suffering from dementia is drastically …

Neuroproteomics: How a Multitude of Proteins Reflect Brain Functions

OA Gomazkov - Biology Bulletin Reviews, 2021 - Springer
The review highlights recent reports of advances in quantitative neuroproteomics that use
new methods to analyze brain functions. Functional neuroproteomics provides new insight …

Neuroproteomic profiling of human body fluids

A Häggmark, JM Schwenk… - PROTEOMICS–Clinical …, 2016 - Wiley Online Library
Analysis of protein expression and abundance provides a possibility to extend the current
knowledge on disease‐associated processes and pathways. The human brain is a complex …

Advances in human brain proteomics analysis of neurodegenerative diseases

Y Chen, X Wang, B Xu - Human Brain, 2022 - eaapublishing.org
Neurodegenerative diseases are characterized by progressive loss of neurons manifested
as motor dysfunction and/or cognitive decline. Aberrant protein aggregation with altered …

Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative disease

WM Caudle, S Pan, M Shi, T Quinn… - PROTEOMICS …, 2008 - Wiley Online Library
Proteomics has revealed itself as a powerful tool in the identification and determination of
proteins and their biological significance. More recently, several groups have taken …

Approaches for targeted proteomics and its potential applications in neuroscience

S Sethi, D Chourasia, IS Parhar - Journal of biosciences, 2015 - Springer
An extensive guide on practicable and significant quantitative proteomic approaches in
neuroscience research is important not only because of the existing overwhelming …