[HTML][HTML] Long-term space flight simulation reveals infradian rhythmicity in human Na+ balance

N Rakova, K Jüttner, A Dahlmann, A Schröder, P Linz… - Cell metabolism, 2013 - cell.com
The steady-state concept of Na+ homeostasis, based on short-term investigations of
responses to high salt intake, maintains that dietary Na+ is rapidly eliminated into urine …

Agreement between 24-hour salt ingestion and sodium excretion in a controlled environment

K Lerchl, N Rakova, A Dahlmann, M Rauh, U Goller… - …, 2015 - Am Heart Assoc
Accurately collected 24-hour urine collections are presumed to be valid for estimating salt
intake in individuals. We performed 2 independent ultralong-term salt balance studies …

Mechanisms of sodium balance: total body sodium, surrogate variables, and renal sodium excretion

P Bie - … Journal of Physiology-Regulatory, Integrative and …, 2018 - journals.physiology.org
The classical concepts of human sodium balance include 1) a total pool of Na+ of≈ 4,200
mmol (total body sodium, TBS) distributed primarily in the extracellular fluid (ECV) and bone …

[HTML][HTML] High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation

K Kitada, S Daub, Y Zhang, JD Klein… - The Journal of …, 2017 - Am Soc Clin Investig
BACKGROUND. The idea that increasing salt intake increases drinking and urine volume is
widely accepted. We tested the hypothesis that an increase in salt intake of 6 g/d would …

[HTML][HTML] Increased salt consumption induces body water conservation and decreases fluid intake

N Rakova, K Kitada, K Lerchl… - The Journal of …, 2017 - Am Soc Clin Investig
BACKGROUND. The idea that increasing salt intake increases drinking and urine volume is
widely accepted. We tested the hypothesis that an increase in salt intake of 6 g/d would …

[HTML][HTML] Spooky sodium balance

J Titze, A Dahlmann, K Lerchl, C Kopp, N Rakova… - Kidney international, 2014 - Elsevier
Current teaching states that when sodium intake is increased from low to high levels, total-
body sodium (TBNa) and water increase until daily sodium excretion again equals intake …

Long-term sodium balance in humans in a terrestrial space station simulation study

J Titze, A Maillet, R Lang, HC Gunga… - American Journal of …, 2002 - Elsevier
Background: Sodium accumulation has been considered to take place in the extracellular
space, leading to water retention and weight gain. This traditional view has been questioned …

[HTML][HTML] Ultra-long–term human salt balance studies reveal interrelations between sodium, potassium, and chloride intake and excretion

A Birukov, N Rakova, K Lerchl, RHGO Engberink… - The American journal of …, 2016 - Elsevier
Background: The intake of sodium, chloride, and potassium is considered important to
healthy nutrition and cardiovascular disease risk. Estimating the intake of these electrolytes …

Sodium balance is not just a renal affair

J Titze - Current opinion in nephrology and hypertension, 2014 - journals.lww.com
Sodium balance is not just a renal affair : Current Opinion in Nephrology and Hypertension
Sodium balance is not just a renal affair : Current Opinion in Nephrology and Hypertension Log in …

Determinants of water and sodium intake and output

AE Stanhewicz, W Larry Kenney - Nutrition reviews, 2015 - academic.oup.com
Physiological regulation of sodium and water intake and output is required for the
maintenance of homeostasis. The behavioral and neuroendocrine mechanisms that govern …