Retroviral assembly is driven by multiple interactions mediated by the Gag polyprotein, the
main structural component of the forming viral shell. Critical determinants of Gag …

Assembly of the HIV and other retroviruses is primarily driven by the oligomerization of the
Gag polyprotein, the major viral structural protein capable of forming virus-like particles even …

Abstract Ivanov et al.(2005) recently reported the structure of a mammalian SCAN domain.
The molecule is a structural homolog of the HIV-1 capsid protein and forms a domain …

In maturing retroviral virions, CA protein assembles to form a capsid shell that is essential for
infectivity. The structure of the two folded domains [N-terminal domain (NTD) and C-terminal …

The capsid protein (CA) of HIV‐1 is composed of two domains, the N‐terminal domain (NTD)
and the C‐terminal domain (CTD). During the assembly of the immature HIV‐1 particle, both …

HIV Gag assembly is the first and most essential step in the formation of virus particles.
Following protein synthesis, Gag relocates from ribosomes and forms a virus particle at the …

Expression of a retroviral protein, Gag, in mammalian cells is sufficient for assembly of
immature virus-like particles (VLPs). VLP assembly is mediated largely by interactions …

The Gag polyprotein is the building block of retroviral particles and its expression is sufficient
for assembly in cells. In HIV-1, nucleic acid (NA) is required for recombinant Gag molecules …

During retrovirus particle assembly and morphogenesis, the retrovirus structural (Gag)
proteins organize into two different arrangements: an immature form assembled by …

The human immunodeficiency virus type 1 (HIV-1) Gag precursor protein Pr55Gag drives
the assembly and release of virus-like particles in the infected cell. The capsid (CA) domain …