Structural basis for the carbohydrate specificities of artocarpin: variation in the length of a loop as a strategy for generating ligand specificity

AA Jeyaprakash, A Srivastav, A Surolia… - Journal of molecular …, 2004 - Elsevier
Artocarpin, a tetrameric lectin of molecular mass 65 kDa, is one of the two lectins extracted
from the seeds of jackfruit. The structures of the complexes of artocarpin with mannotriose …

Crystal structures of artocarpin, a Moraceae lectin with mannose specificity, and its complex with methyl-α-D-mannose: implications to the generation of carbohydrate …

JV Pratap, AA Jeyaprakash, PG Rani, K Sekar… - Journal of molecular …, 2002 - Elsevier
The seeds of jack fruit (Artocarpus integrifolia) contain two tetrameric lectins, jacalin and
artocarpin. Jacalin was the first lectin found to exhibit the β-prism I fold, which is …

KM+, a mannose-binding lectin from Artocarpus integrifolia: amino acid sequence, predicted tertiary structure, carbohydrate recognition, and analysis of the β-prism …

JC Rosa, PSL DE OLIVEIRA, R Garratt, L Beltramini… - Protein …, 1999 - cambridge.org
The complete amino acid sequence of the lectin KM+ from Artocarpus integrifolia (jackfruit),
which contains 149 residues/mol, is reported and compared to those of other members of …

Structural basis for the energetics of jacalin–sugar interactions: promiscuity versus specificity

AA Jeyaprakash, G Jayashree, SK Mahanta… - Journal of molecular …, 2005 - Elsevier
Jacalin, a tetrameric lectin, is one of the two lectins present in jackfruit (Artocarpus
integrifolia) seeds. Its crystal structure revealed, for the first time, the occurrence of the β …

Structural basis for the unusual carbohydrate-binding specificity of jacalin towards galactose and mannose

Y Bourne, CH Astoul, V Zamboni… - Biochemical …, 2002 - portlandpress.com
Evidence is presented that the specificity of jacalin, the seed lectin from jack fruit (Artocarpus
integrifolia), is not directed exclusively against the T-antigen disaccharide Galβ1, 3GalNAc …

Artocarpin is a polyspecific jacalin-related lectin with a monosaccharide preference for mannose

A Barre, WJ Peumans, M Rossignol, G Borderies… - Biochimie, 2004 - Elsevier
A reinvestigation of the carbohydrate-binding properties revealed that artocarpin, a
previously described mannose-specific lectin from jackfruit (Artocarpus integrifolia) seeds …

Structural basis of oligomannose recognition by the Pterocarpus angolensis seed lectin

R Loris, I Van Walle, H De Greve, S Beeckmans… - Journal of molecular …, 2004 - Elsevier
The crystal structure of a Man/Glc-specific lectin from the seeds of the bloodwood tree
(Pterocarpus angolensis), a leguminous plant from central Africa, has been determined in …

Isothermal titration calorimetric studies on the binding of deoxytrimannoside derivatives with artocarpin: implications for a deep-seated combining site in lectins

PG Rani, K Bachhawat, GB Reddy, S Oscarson… - Biochemistry, 2000 - ACS Publications
The carbohydrate binding specificity of the seed lectin from Artocarpus integrifolia,
artocarpin, has been elucidated by the enzyme-linked lectin absorbent assay [Misquith, S …

Insights into carbohydrate recognition by Narcissus pseudonarcissus lectin: the crystal structure at 2 Å resolution in complex with α1-3 mannobiose

MK Sauerborn, LM Wright, CD Reynolds… - Journal of molecular …, 1999 - Elsevier
Carbohydrate recognition by monocot mannose-binding lectins was studied via the crystal
structure determination of daffodil (Narcissus pseudonarcissus) lectin. The lectin was …

Two orthorhombic crystal structures of a galactose-specific lectin from Artocarpus hirsuta in complex with methyl-α-D-galactose

KN Rao, CG Suresh, UV Katre… - … Section D: Biological …, 2004 - journals.iucr.org
Based on their carbohydrate specificity, the jacalin family of lectins can be divided into two
groups: galactose-specific and mannose-specific. The former are cytoplasmic proteins …