[HTML][HTML] Inflammasomes and colorectal cancer

SK Shahbaz, K Koushki, SH Ayati, AR Bland… - Cells, 2021 - ncbi.nlm.nih.gov
Inflammasomes are important intracellular multiprotein signaling complexes that modulate
the activation of caspase-1 and induce levels of the proinflammatory cytokines interleukin-1β …

[HTML][HTML] Inflammasomes and colorectal cancer

S Keshavarz Shahbaz, K Koushki, SH Ayati, AR Bland… - Cells, 2021 - mdpi.com
Inflammasomes are important intracellular multiprotein signaling complexes that modulate
the activation of caspase-1 and induce levels of the proinflammatory cytokines interleukin-1β …

[HTML][HTML] Inflammasomes and cancer: the dynamic role of the inflammasome in tumor development

M Kantono, B Guo - Frontiers in immunology, 2017 - frontiersin.org
Chronic Inflammation in tumor microenvironments is not only associated with various stages
of tumor development, but also has significant impacts on tumor immunity and …

Inflammasome signaling in colorectal cancer

BR Sharma, TD Kanneganti - Translational Research, 2023 - Elsevier
Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths in the world.
Inflammation is often an underlying risk factor for developing CRC. Maintaining gut …

[HTML][HTML] Inflammasomes in inflammation-induced cancer

C Lin, J Zhang - Frontiers in immunology, 2017 - frontiersin.org
The inflammasome is an important multiprotein complex that functions during inflammatory
immune responses. The activation of inflammasome will lead to the autoactivation of …

Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation

B Hu, E Elinav, RA Flavell - Cell Cycle, 2011 - Taylor & Francis
Chronic inflammation is a risk factor for many types of human cancers, yet the precise
mechanism of this strong association is largely unknown. The inflammasome is a …

Diverging inflammasome signals in tumorigenesis and potential targeting

R Karki, TD Kanneganti - Nature Reviews Cancer, 2019 - nature.com
Inflammasomes are molecular platforms that assemble upon sensing various intracellular
stimuli. Inflammasome assembly leads to activation of caspase 1, thereby promoting the …

[HTML][HTML] Focus: organelles: inflammasomes in colitis and colorectal cancer: mechanism of action and therapies

A Pandey, C Shen, SM Man - The Yale journal of biology and …, 2019 - ncbi.nlm.nih.gov
Colorectal cancer is a multifactorial disease and a leading cause of cancer-related deaths
worldwide. Inflammation is a driver across multiple stages in the development of colorectal …

Inflammasomes and intestinal tumorigenesis

MH Zaki, M Lamkanfi, TD Kanneganti - Drug Discovery Today: Disease …, 2011 - Elsevier
Colorectal cancer is a major health problem in developed countries. Chronic intestinal
inflammation predisposes individuals to the development of colorectal cancer. The …

Inflammasomes in intestinal inflammation and cancer

GY Chen, G Núñez - Gastroenterology, 2011 - Elsevier
Inflammasomes are multi-protein complexes that mediate activation of caspase-1, which
promotes secretion of the proinflammatory cytokines interleukin-1β and interleukin-18 and …