Identification of an Anti‐inflammation protein, Annexin A1, in tendon derived stem cells (TDSCs) of cystic fibrosis mice: a comparative proteomic analysis

Y Liu, L Feng, H Wang, Y Wang… - PROTEOMICS …, 2018 - Wiley Online Library
Purpose: A previous study reported an elevated inflammation during tendon injury in mice
with cystic fibrosis (CF), indicating the inadequate management of inflammation due to …

[HTML][HTML] Down-regulation of the Anti-inflammatory protein annexin A1 in cystic fibrosis Knock-out mice and patients* S

N Bensalem, AP Ventura, B Vallée, J Lipecka… - Molecular & Cellular …, 2005 - ASBMB
Cystic fibrosis is a fatal human genetic disease caused by mutations in the CFTR gene
encoding a cAMP-activated chloride channel. It is characterized by abnormal fluid transport …

[HTML][HTML] Recombinant human annexin A5 accelerates diabetic wounds healing by regulating skin inflammation

B Kang, Z Jia, Y Dong, W Li, W Zhang - Regenerative Therapy, 2024 - Elsevier
Background One of the key obstacles to the healing of diabetic wound is the persistence of
active inflammation. We previously demonstrated the potential of cell-free fat extract …

[HTML][HTML] An immunocytochemical and in situ hybridization analysis of annexin 1 expression in rat mast cells: modulation by inflammation and dexamethasone

SM Oliani, HC Christian, J Manston, RJ Flower… - Laboratory …, 2000 - nature.com
The presence and localization of the anti-inflammatory protein annexin 1 (also known as
lipocortin 1) in perivenular rat mast cells was investigated here. Using the rat mesenteric …

Reciprocal regulation of pro-inflammatory Annexin A2 and anti-inflammatory Annexin A1 in the pathogenesis of rheumatoid arthritis

V Haridas, P Shetty, E Sarathkumar, A Bargale… - Molecular biology …, 2019 - Springer
Annexin A2 has been implicated in several immune modulated diseases including
Rheumatoid arthritis (RA) pannus formation. The most relied treatment option for RA …

[HTML][HTML] Therapeutic potential for targeting Annexin A1 in fibrotic diseases

Z Yan, X Cheng, T Wang, X Hong, G Shao, C Fu - Genes & Diseases, 2022 - Elsevier
Annexin A1, a well-known endogenous anti-inflammatory mediator, plays a critical role in a
variety of pathological processes. Fibrosis is described by a failure of tissue regeneration …

[HTML][HTML] Proteomic identification of an upregulated isoform of annexin A3 in the spinal cords of rats in a neuropathic pain model

W Zou, W Xu, Z Song, T Zhong, Y Weng… - Frontiers in …, 2017 - frontiersin.org
Neuropathic pain (NP) is induced by nerve damage or a disturbance in the peripheral or
central nervous systems. Nerve damage causes the activation of sensitizing mechanisms in …

Deficiency of annexin A1 in CD4+ T cells exacerbates T cell–dependent inflammation

YH Yang, W Song, JA Deane, W Kao… - The Journal of …, 2013 - journals.aai.org
Abstract Annexin A1 (AnxA1) is recognized as an endogenous anti-inflammatory molecule.
However, its effects on the adaptive immune response and, in particular, on T cells remain …

Modulation of the endogenous Annexin A1 in a cigarette smoke cessation model: Potential therapeutic target in reversing the damage caused by smoking?

ISL Lebron, LF da Silva, JT Paletta, RA da Silva… - … -Research and Practice, 2019 - Elsevier
Background Smoking cessation may help in the reversal of inflammation and damage
caused by smoking. The endogenous annexin A1 (AnxA1) protein has anti-inflammatory …

Annexin A6 interacts with p65 and stimulates NF‐κB activity and catabolic events in articular chondrocytes

KA Campbell, T Minashima, Y Zhang… - Arthritis & …, 2013 - Wiley Online Library
Objective ANXA6, the gene for annexin A6, is highly expressed in osteoarthritic (OA)
articular chondrocytes but not in healthy articular chondrocytes. This study was undertaken …