[HTML][HTML] Toward overcoming treatment failure in rheumatoid arthritis

Z Wang, J Huang, D Xie, D He, A Lu… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by inflammation and
bone erosion. The exact mechanism of RA is still unknown, but various immune cytokines …

[HTML][HTML] Management of rheumatoid arthritis: an overview

AF Radu, SG Bungau - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease of unknown etiology,
primarily affecting the joints, then extra-articular manifestations can occur. Due to its …

Treatment of rheumatoid arthritis: unraveling the conundrum

E Zampeli, PG Vlachoyiannopoulos, AG Tzioufas - Journal of autoimmunity, 2015 - Elsevier
Rheumatoid arthritis (RA) is a heterogeneous disease with a complex and yet not fully
understood pathophysiology, where numerous different cell-types contribute to a destructive …

A broad look into the future of rheumatoid arthritis

J Mucke, M Krusche… - Therapeutic Advances in …, 2022 - journals.sagepub.com
Despite all improvements in rheumatoid arthritis, we are still not able to prevent or cure the
disease. Diagnostic delays due to lack of access to a specialist and costly therapies are still …

New insights into the pathogenesis and management of rheumatoid arthritis

S Jin, J Zhao, M Li, X Zeng - Chronic Diseases and Translational …, 2022 - mednexus.org
Over the past few decades, understanding of the pathogenesis of rheumatoid arthritis (RA)
has improved substantially. Insights into the cellular and molecular mechanisms involved in …

[HTML][HTML] Biomarkers to predict DMARDs efficacy and adverse effect in rheumatoid arthritis

K Wei, P Jiang, J Zhao, Y Jin, R Zhang… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA), one of the most common immune system diseases, mainly affects
middle-aged and elderly individuals and has a serious impact on the quality of life of …

Rheumatoid arthritis: a case for personalized health care?

MA Karsdal, AC Bay‐Jensen, K Henriksen… - Arthritis care & …, 2014 - Wiley Online Library
Ethical, clinical, and economic considerations highlight the pressing need to advance the
identification of optimal treatments for each individual patient. Personalized health care …

[HTML][HTML] Lessons from the success and failure of targeted drugs for rheumatoid arthritis: perspectives for effective basic and translational research

M Kim, Y Choe, S Lee - Immune Network, 2022 - ncbi.nlm.nih.gov
Rheumatoid arthritis (RA) is a representative autoimmune disease that is primarily
characterized by persistent inflammation and progressive destruction of synovial joints. RA …

An update on novel therapeutic intervention in Rheumatoid arthritis

P Shah, A Siddique, A Thakkar, S Gharat… - International …, 2022 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disorder that is slow progressive destruction of
the joints and is caused by autoantibodies that target a variety of organs thereby leading to …

A paradigm shift in rheumatoid arthritis over the past decade

Y Kaneko, T Takeuchi - Internal Medicine, 2014 - jstage.jst.go.jp
Recent advances have improved our understanding of the pathogenesis of rheumatoid
arthritis (RA), and the development of new therapeutics, including biological agents, have …