Exploiting genomic surveillance to map the spatio-temporal dispersal of SARS-CoV-2 spike mutations in Belgium across 2020

N Bollen, M Artesi, K Durkin, SL Hong, B Potter… - Scientific reports, 2021 - nature.com
At the end of 2020, several new variants of SARS-CoV-2—designated variants of concern—
were detected and quickly suspected to be associated with a higher transmissibility and …

Improved SARS-CoV-2 sequencing surveillance allows the identification of new variants and signatures in infected patients

A Grimaldi, F Panariello, P Annunziata, T Giuliano… - Genome Medicine, 2022 - Springer
Background Genomic surveillance of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is the only approach to rapidly monitor and tackle emerging variants of …

SARS-CoV-2 genome surveillance in Mainz, Germany, reveals convergent origin of the N501Y spike mutation in a hospital setting

NA Lemmermann, B Lieb, T Laufs, A Renzaho… - medRxiv, 2021 - medrxiv.org
While establishing a regional SARS-Cov-2 variant surveillance by genome sequencing, we
have identified three infected individuals in a clinical setting (two long-term hospitalized …

Two years of genomic surveillance in Belgium during the SARS-CoV-2 pandemic to attain country-wide coverage and monitor the introduction and spread of emerging …

L Cuypers, S Dellicour, SL Hong, BI Potter… - Viruses, 2022 - mdpi.com
An adequate SARS-CoV-2 genomic surveillance strategy has proven to be essential for
countries to obtain a thorough understanding of the variants and lineages being imported …

SARS-CoV-2 variants of concern and spike protein mutational dynamics in a Swedish cohort during 2021, studied by Nanopore sequencing

S Mannsverk, J Bergholm, N Palanisamy, P Ellström… - Virology Journal, 2022 - Springer
Background Since the beginning of the COVID-19 pandemic, new variants of significance to
public health have emerged. Consequently, early detection of new mutations and variants …

[HTML][HTML] Genomic surveillance of SARS-CoV-2 evolution by a centralised pipeline and weekly focused sequencing, Austria, January 2021 to March 2023

O Frank, DA Balboa, M Novatchkova, E Özkan… - …, 2024 - eurosurveillance.org
Background The COVID-19 pandemic was largely driven by genetic mutations of SARS-CoV-
2, leading in some instances to enhanced infectiousness of the virus or its capacity to evade …

[HTML][HTML] Surveillance for variants of SARS-CoV-2 to inform risk assessments

HA Cohen, S Mesfin, J Ikejezie… - Bulletin of the World …, 2023 - ncbi.nlm.nih.gov
Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, numerous
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have emerged …

Low testing rates limit the ability of genomic surveillance programs to monitor SARS-CoV-2 variants: a mathematical modelling study

AX Han, A Toporowski, JA Sacks, M Perkins, S Briand… - medRxiv, 2022 - medrxiv.org
Background Genomic surveillance is essential for monitoring the emergence and spread of
SARS-CoV-2 variants. SARS-CoV-2 diagnostic testing is the starting point for SARS-CoV-2 …

A Sanger-based approach for scaling up screening of SARS-CoV-2 variants of interest and concern

MF Bezerra, LC Machado, VCV De Carvalho… - Infection, Genetics and …, 2021 - Elsevier
The global spread of new SARS-CoV-2 variants of concern underscore an urgent need of
simple deployed molecular tools that can differentiate these lineages. Several tools and …

[HTML][HTML] Freely accessible ready to use global infrastructure for SARS-CoV-2 monitoring

W Maier, S Bray, M van den Beek, D Bouvier, N Coraor… - BioRxiv, 2021 - ncbi.nlm.nih.gov
The COVID-19 pandemic is the first global health crisis to occur in the age of big genomic
data. Although data generation capacity is well established and sufficiently standardized …