A proteomic analysis of the early secondary molecular effects caused by Cn2 scorpion toxin on neuroblastoma cells
Although the primary physiological effects produced by scorpion toxins are already well
known, most of the secondary molecular events following scorpion neurotoxins–ion channel …
known, most of the secondary molecular events following scorpion neurotoxins–ion channel …
Activation of sodium channel by a novel α-scorpion toxin, BmK NT2, stimulates ERK1/2 and CERB phosphorylation through a Ca2+ dependent pathway in neocortical …
X Zou, Y Wu, J Chen, F Zhao, F Zhang, B Yu… - International Journal of …, 2017 - Elsevier
Neuronal excitability controls the expression of a variety of genes and proteins and therefore
regulates neurite outgrowth and synapse formation, fundamental physiological processes …
regulates neurite outgrowth and synapse formation, fundamental physiological processes …
Activation of sodium channels by α-scorpion toxin, BmK NT1, produced neurotoxicity in cerebellar granule cells: an association with intracellular Ca2+ overloading
Y He, X Zou, X Li, J Chen, L Jin, F Zhang, B Yu… - Archives of …, 2017 - Springer
Voltage-gated sodium channels (VGSCs) are responsible for the action potential generation
in excitable cells including neurons and involved in many physiological and pathological …
in excitable cells including neurons and involved in many physiological and pathological …
NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical β‐toxin sequence but with α‐like physiological activity
F del Río‐Portilla, E Hernández‐Marín… - European journal of …, 2004 - Wiley Online Library
Cn12 isolated from the venom of the scorpion Centruroides noxius has 67 amino‐acid
residues, closely packed with four disulfide bridges. Its primary structure and disulfide …
residues, closely packed with four disulfide bridges. Its primary structure and disulfide …
[PDF][PDF] Independent origins of scorpion toxins affecting potassium and sodium channels
S Zhang, B Gao, S Zhu - 2018 - ir.ioz.ac.cn
In recent years, the field of toxinology has expanded substantially. On the one hand it
studies venomous animals, plants and micro organisms in detail to understand their mode of …
studies venomous animals, plants and micro organisms in detail to understand their mode of …
Electrophysiological characterization of BmK I, an α-like scorpion toxin, on rNav1. 5 expressed in HEK293t cells
XH Feng, JX Chen, Y Liu, YH Ji - Toxicology in Vitro, 2008 - Elsevier
A recent study described the pharmacological properties of BmK I, an α-like toxin from the
Chinese scorpion Buthus martensi Karsch, on the cardiac sodium channel (hH1) expressed …
Chinese scorpion Buthus martensi Karsch, on the cardiac sodium channel (hH1) expressed …
Evidence for the existence of a common ancestor of scorpion toxins affecting ion channels
C Zhijian, W Yingliang, S Jiqun… - … of biochemical and …, 2003 - Wiley Online Library
All scorpion toxins from different 30 species are simply reviewed. A new classification
system of scorpion toxins is first proposed: scorpion toxins are classified into three families …
system of scorpion toxins is first proposed: scorpion toxins are classified into three families …
Identification of structural elements of a scorpion α-neurotoxin important for receptor site recognition
N Zilberberg, O Froy, E Loret, S Cestele, D Arad… - Journal of Biological …, 1997 - ASBMB
α-Neurotoxins from scorpion venoms constitute the most studied group of modifiers of the
voltage-sensitive sodium channels, and yet, their toxic site has not been characterized. We …
voltage-sensitive sodium channels, and yet, their toxic site has not been characterized. We …
Scorpion toxins to unravel the conundrum of ion channel structure and functioning
E Ortiz, LD Possani - Toxicon, 2018 - Elsevier
The consequences of scorpion stings on the affected victims, including humans, have been
known since ancient times. The effects of the venom, first on neurotransmission and …
known since ancient times. The effects of the venom, first on neurotransmission and …
Isolation, characterization and comparison of a novel crustacean toxin with a mammalian toxin from the venom of the scorpion Centruroides noxius Hoffmann
C Garcı́a, B Becerril, B Selisko, M Delepierre… - … and Physiology Part B …, 1997 - Elsevier
A novel crustacean-specific toxin, Cn5, containing 66 amino acid residues was isolated from
the venom of the scorpion Centruroides noxius Hoffmann. It is stabilized by four disulfide …
the venom of the scorpion Centruroides noxius Hoffmann. It is stabilized by four disulfide …