Biotransformation of brominated flame retardants into potentially endocrine‐disrupting metabolites, with special attention to 2, 2′, 4, 4′‐tetrabromodiphenyl ether …
T Hamers, JH Kamstra, E Sonneveld… - Molecular nutrition & …, 2008 - Wiley Online Library
In this study, the endocrine‐disrupting (ED) potency of metabolites from brominated flame
retardants (BFRs) was determined. Metabolites were obtained by incubating single‐parent …
retardants (BFRs) was determined. Metabolites were obtained by incubating single‐parent …
In Vitro Profiling of the Endocrine-Disrupting Potency of Brominated Flame Retardants
T Hamers, JH Kamstra, E Sonneveld… - Toxicological …, 2006 - academic.oup.com
Over the last few years, increasing evidence has become available that some brominated
flame retardants (BFRs) may have endocrine-disrupting (ED) potencies. The goal of the …
flame retardants (BFRs) may have endocrine-disrupting (ED) potencies. The goal of the …
Inhibition and induction of aromatase (CYP19) activity by brominated flame retardants in H295R human adrenocortical carcinoma cells
RF Cantón, JT Sanderson, RJ Letcher… - Toxicological …, 2005 - academic.oup.com
Brominated flame retardants (BFRs) are persistent and ubiquitous chemicals in the
environment, and they are found at increasing levels in tissues of wildlife and humans …
environment, and they are found at increasing levels in tissues of wildlife and humans …
In vitro endocrine disruption and TCDD-like effects of three novel brominated flame retardants: TBPH, TBB, & TBCO
DMV Saunders, EB Higley, M Hecker, R Mankidy… - Toxicology letters, 2013 - Elsevier
The novel brominated flame retardants (NBFRs), 2-ethylhexyl-2, 3, 4, 5-tetrabromobenzoate
(TBB), Bis (2-ethylhexyl)-2, 3, 4, 5-tetrabromophtalate (TBPH), and 1, 2, 5, 6 …
(TBB), Bis (2-ethylhexyl)-2, 3, 4, 5-tetrabromophtalate (TBPH), and 1, 2, 5, 6 …
New insights into the endocrine disrupting effects of brominated flame retardants
J Legler - Chemosphere, 2008 - Elsevier
The objective of this review is to provide an overview of recent studies demonstrating the
endocrine disrupting (ED) effects of brominated flame retardants (BFRs), while highlighting …
endocrine disrupting (ED) effects of brominated flame retardants (BFRs), while highlighting …
Brominated flame retardants and endocrine disruption
JG Vos, G Becher, M Van Den Berg… - Pure and Applied …, 2003 - degruyter.com
From an environmental point of view, an increasing important group of organohalogen
compounds are the brominated flame retardants (BFRs), which are widely used in polymers …
compounds are the brominated flame retardants (BFRs), which are widely used in polymers …
Are brominated flame retardants endocrine disruptors?
J Legler, A Brouwer - Environment international, 2003 - Elsevier
Brominated flame retardants (BFRs) are a group of compounds that have received much
attention recently due to their similarity with “old” classes of organohalogenated compounds …
attention recently due to their similarity with “old” classes of organohalogenated compounds …
Impacts of unregulated novel brominated flame retardants on human liver thyroid deiodination and sulfotransferation
The inhibitory effects of five novel brominated flame retardants, 1, 2-bis (2, 4, 5-
tribromophenoxy) ethane (BTBPE), decabromodiphenylethane (DBDPE), 2-ethylhexyl-2, 3 …
tribromophenoxy) ethane (BTBPE), decabromodiphenylethane (DBDPE), 2-ethylhexyl-2, 3 …
Brominated flame retardants as possible endocrine disrupters
PO Darnerud - International journal of andrology, 2008 - Wiley Online Library
Brominated flame retardants (BFR) are endocrine disrupters in experimental systems, both
in vitro and in vivo. Although BFR effects on thyroid hormones are well confirmed, studies of …
in vitro and in vivo. Although BFR effects on thyroid hormones are well confirmed, studies of …
Effects of chronic exposure to an environmentally relevant mixture of brominated flame retardants on the reproductive and thyroid system in adult male rats
SR Ernest, MG Wade, C Lalancette, YQ Ma… - Toxicological …, 2012 - academic.oup.com
Brominated flame retardants (BFRs) are incorporated into a wide variety of consumer
products, are readily released into home and work environments, and are present in house …
products, are readily released into home and work environments, and are present in house …