Outcomes for patients with mCRPC and liver metastasis receiving 177-Lu-PSMA-617 treatment.

M Muniz, AO Sartor, AM Mahmoud, J Orme, JY Kwon… - 2024 - ascopubs.org
175 Background: It is well-known that patients with liver metastases from metastatic
castration resistant prostate cancer (mCRPC) have poorer or transient responses to many …

Response and outcome of liver metastases in patients with metastatic castration-resistant prostate cancer (mCRPC) undergoing 177Lu-PSMA-617 radioligand …

F Khreish, N Kochems, F Rosar, A Sabet… - European journal of …, 2021 - Springer
Purpose Little is known about the efficacy of prostate-specific membrane antigen (PSMA)–
targeted radioligand therapy (RLT) against liver metastases of metastatic castration-resistant …

Real world data of 177 Lutetium-PSMA-617 for metastatic castration resistant prostate cancer (mCRPC): Analysis of patients treated from 2 large reference centers.

HF Bruzzi, D Herchenhorn, GCK Lopes, H Bekierman… - 2024 - ascopubs.org
e17050 Background: 177Lu-PSMA-617 was recently approved for the treatment of patients
with mCRPC in the USA. While treatment is associated with improved survival, responses to …

1P Is 177Lu-PSMA an effective treatment modality for mCRPC patients with visceral metastasis?

M Gupta, PS Choudhury, A Singh… - Annals of …, 2021 - annalsofoncology.org
Background Metastatic castration-resistant prostate cancer (mCRPC) is the most
challenging stage in prostate cancer. Patient with visceral metastasis have the poorest …

Cost-Effectiveness Analysis of 177Lu-PSMA-617 Radioligand Therapy in Metastatic Castration-Resistant Prostate Cancer

W Kunz, D Mehrens, K Kramer, L Unterrainer, L Beyer… - 2022 - Soc Nuclear Med
2551 Introduction: Metastatic castration-resistant prostate cancer (mCRPC) poses a
therapeutic challenge with poor prognosis. The VISION trial demonstrated prolonged overall …

Additional local therapy of liver metastases in mCRPC patients receiving systemic PSMA targeted therapy

R Seifert, K Kessel, M Boegemann… - Journal of Nuclear …, 2019 - Soc Nuclear Med
The aim of this study was to evaluate the efficacy of 177 Lu-PSMA-617 (Lu-PSMA) and
Selective Internal Radiation Therapy (SIRT) for the treatment of liver metastases of castration …

Additional local therapy for liver metastases in patients with metastatic castration-resistant prostate cancer receiving systemic PSMA-targeted therapy

R Seifert, K Kessel, M Boegemann… - Journal of Nuclear …, 2020 - Soc Nuclear Med
The aim of this study was to evaluate the efficacy of 177Lu-prostate-specific membrane
antigen (PSMA)-617 (177Lu-PSMA) and selective internal radiation therapy (SIRT) for the …

[HTML][HTML] Second line chemotherapy and visceral metastases are associated with poor survival in patients with mCRPC receiving 177Lu-PSMA-617

K Kessel, R Seifert, M Schäfers, M Weckesser… - Theranostics, 2019 - ncbi.nlm.nih.gov
The purpose of this study was to identify previous treatments and biomarker profile features
that prognosticate overall survival (OS) in patients with mCRPC receiving 177 Lu-PSMA …

VISION: An international, prospective, open-label, multicenter, randomized phase 3 study of 177Lu-PSMA-617 in the treatment of patients with progressive PSMA …

AO Sartor, MJ Morris, BJ Krause - 2019 - ascopubs.org
TPS5099 Background: The novel therapeutic drug 177Lu-PSMA-617 is a prostate specific
membrane antigen (PSMA) targeting agent to deliver radionuclide therapy for the treatment …

Lutetium-177–PSMA-617 for metastatic castration-resistant prostate cancer

O Sartor, J De Bono, KN Chi, K Fizazi… - … England Journal of …, 2021 - Mass Medical Soc
Background Metastatic castration-resistant prostate cancer remains fatal despite recent
advances. Prostate-specific membrane antigen (PSMA) is highly expressed in metastatic …