Background—Hypertension is associated with impaired glucose metabolism and insulin
resistance. Chronic activation of the sympathetic nervous system may contribute to either …

Increased central sympathetic drive is a hallmark of several important clinical conditions
including essential hypertension, heart failure, chronic kidney disease, and insulin …

Background Catheter‐based renal sympathetic denervation (CRD) is associated with
significant blood pressure (BP) reductions in patients with severe therapy‐resistant …

Hypertension imposes a major burden of morbidity and mortality and is associated with
sympathetic nervous system overactivity. Renal sympathetic denervation has been shown to …

BACKGROUND: Activation of renal sympathetic nerves is key to pathogenesis of essential
hypertension. We aimed to assess effectiveness and safety of catheter-based renal …

Background—Renal sympathetic nerve activation contributes to the pathogenesis of
hypertension. Symplicity HTN-2, a multicenter, randomized trial, demonstrated that catheter …

Renal sympathetic hyperactivity is seminal in the maintenance and progression of
hypertension. Catheter-based renal sympathetic denervation has been shown to …

Few data are available with regard to the effectiveness of renal sympathetic denervation in
patients with resistant hypertension yet only mildly elevated blood pressure (BP). Patients …

Percutaneous renal sympathetic denervation by radiofrequency energy has been reported
to reduce blood pressure (BP) by the reduction of renal sympathetic efferent and afferent …

Renal sympathetic denervation has shown promise in treating hypertension resistant to drug
therapy. This procedure lowers blood pressure via targeted attenuation of renal sympathetic …