Age-related differences in diagnostic accuracy of plasma glial fibrillary acidic protein and tau for identifying acute intracranial trauma on computed tomography: a …

RC Gardner, R Rubenstein, KKW Wang… - Journal of …, 2018 - liebertpub.com
Plasma tau and glial fibrillary acidic protein (GFAP) are promising biomarkers for identifying
traumatic brain injury (TBI) patients with intracranial trauma on computed tomography (CT) …

Predictive performance of traumatic brain injury biomarkers in high-risk elderly patients

MD Ward, A Weber, VRD Merrill… - The journal of …, 2020 - academic.oup.com
Background Serum glial fibrillary acidic protein (GFAP) and ubiquitin carboxyl-terminal
esterase L1 (UCH-L1) have recently received US Food and Drug Administration approval for …

Glial fibrillary acidic protein elevations relate to neuroimaging abnormalities after mild TBI

J Gill, L Latour, R Diaz-Arrastia, V Motamedi, C Turtzo… - Neurology, 2018 - AAN Enterprises
Objectives To determine whether a panel of blood-based biomarkers can discriminate
between patients with suspected mild traumatic brain injury (mTBI) with and without …

[HTML][HTML] Comparing glial fibrillary acidic protein (GFAP) in serum and plasma following mild traumatic brain injury in older adults

NA Huebschmann, TM Luoto, JE Karr… - Frontiers in …, 2020 - frontiersin.org
Objective: Identification and validation of blood-based biomarkers for the diagnosis and
prognosis of mild traumatic brain injury (mTBI) is of critical importance. There have been …

Association between blood and computed tomographic imaging biomarkers in a cohort of mild traumatic brain injury patients

H Chen, VY Ding, G Zhu, B Jiang, Y Li… - Journal of …, 2022 - liebertpub.com
The objective of this work was to analyze the relationships between traumatic brain injury
(TBI) on computed tomographic (CT) imaging and blood concentration of glial fibrillary acidic …

[HTML][HTML] Examining four blood biomarkers for the detection of acute intracranial abnormalities following mild traumatic brain injury in older adults

GL Iverson, M Minkkinen, JE Karr, K Berghem… - Frontiers in …, 2022 - frontiersin.org
Blood-based biomarkers have been increasingly studied for diagnostic and prognostic
purposes in patients with mild traumatic brain injury (MTBI). Biomarker levels in blood have …

Correlation of blood biomarkers and biomarker panels with traumatic findings on computed tomography after traumatic brain injury

P PostiJussi, SK TakalaRiikka, M DickensAlex… - Journal of …, 2019 - liebertpub.com
The aim of the study was to examine the ability of eight protein biomarkers and their
combinations in discriminating computed tomography (CT)-negative and CT-positive …

Comparing plasma phospho tau, total tau, and phospho tau–total tau ratio as acute and chronic traumatic brain injury biomarkers

R Rubenstein, B Chang, JK Yue, A Chiu… - JAMA …, 2017 - jamanetwork.com
Importance Annually in the United States, at least 3.5 million people seek medical attention
for traumatic brain injury (TBI). The development of therapies for TBI is limited by the …

Time course and diagnostic accuracy of glial and neuronal blood biomarkers GFAP and UCH-L1 in a large cohort of trauma patients with and without mild traumatic …

L Papa, GM Brophy, RD Welch, LM Lewis… - JAMA …, 2016 - jamanetwork.com
Importance Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-
L1) have been widely studied and show promise for clinical usefulness in suspected …

Glial fibrillary acidic protein (GFAP) outperforms S100 calcium-binding protein B (S100B) and ubiquitin C-terminal hydrolase L1 (UCH-L1) as predictor for positive …

MY Mahan, M Thorpe, A Ahmadi, T Abdallah… - World neurosurgery, 2019 - Elsevier
Objective Traumatic brain injuries (TBIs) are largely underdiagnosed and may have
persistent refractory consequences. Current assessments for acute TBI are limited to …