Collection of nanoliter microdialysate fractions in plugs for off-line in vivo chemical monitoring with up to 2 s temporal resolution

M Wang, T Slaney, O Mabrouk, RT Kennedy - Journal of neuroscience …, 2010 - Elsevier
An off-line in vivo neurochemical monitoring approach was developed based on collecting
nanoliter microdialysate fractions as an array of “plugs” segmented by immiscible oil in a …

Microfluidic electrophoresis chip coupled to microdialysis for in vivo monitoring of amino acid neurotransmitters

ZD Sandlin, M Shou, JG Shackman… - Analytical …, 2005 - ACS Publications
Microfluidic electrophoresis devices were coupled on-line to microdialysis for in vivo
monitoring of primary amine neurotransmitters in rat brain. The devices contained a sample …

Collection, storage, and electrophoretic analysis of nanoliter microdialysis samples collected from awake animals in vivo

M Wang, ND Hershey, OS Mabrouk… - Analytical and …, 2011 - Springer
Microdialysis sampling is an important tool for chemical monitoring in living systems.
Temporal resolution is an important figure of merit that is determined by sampling frequency …

Monitoring neurochemical release from astrocytes using in vitro microdialysis coupled with high-speed capillary electrophoresis

AL Hogerton, MT Bowser - Analytical chemistry, 2013 - ACS Publications
We have developed a novel in vitro approach for monitoring fast neurochemical dynamics in
model cell systems using microdialysis sampling coupled with high-speed capillary …

In vivo monitoring of amino acids by microdialysis sampling with on-line derivatization by naphthalene-2, 3-dicarboxyaldehyde and rapid micellar electrokinetic …

M Shou, AD Smith, JG Shackman, J Peris… - Journal of neuroscience …, 2004 - Elsevier
An analytical method was developed to monitor amino acids collected by in vivo
microdialysis. Microdialysate was continuously derivatized on-line by mixing 6mM …

Microfabrication and in vivo performance of a microdialysis probe with embedded membrane

WH Lee, T Ngernsutivorakul, OS Mabrouk… - Analytical …, 2016 - ACS Publications
Microdialysis sampling is an essential tool for in vivo neurochemical monitoring.
Conventional dialysis probes are over 220 μm in diameter and have limited flexibility in …

Microfluidic chip for low-flow push-pull perfusion sampling in vivo with on-line analysis of amino acids

NA Cellar, ST Burns, JC Meiners, H Chen… - Analytical …, 2005 - ACS Publications
Multilayer soft lithography was used to prepare a poly (dimethylsiloxane) microfluidic chip
that allows for in vivo sampling of amino acid neurotransmitters by low-flow push− pull …

One-second time resolution brain microdialysis in fully awake rats: protocol for the collection, separation and sorting of nanoliter dialysate volumes

S Rossell, LE Gonzalez, L Hernández - Journal of Chromatography B, 2003 - Elsevier
Capillary zone electrophoresis is capable of analyzing nanoliter volumes, reducing the
challenge posed by brain microdialysis time resolution improvement to the management of …

A miniaturized push–pull-perfusion probe for few-second sampling of neurotransmitters in the mouse brain

FTG Van Den Brink, T Phisonkunkasem, A Asthana… - Lab on a Chip, 2019 - pubs.rsc.org
Measuring biomolecule concentrations in the brain of living animals, in real time, is a
challenging task, especially when detailed information at high temporal resolution is also …

High temporal resolution monitoring of glutamate and aspartate in vivo using microdialysis on-line with capillary electrophoresis with laser-induced fluorescence …

MW Lada, TW Vickroy, RT Kennedy - Analytical chemistry, 1997 - ACS Publications
An automated method for high temporal resolution monitoring of the neurotransmitters
glutamate and aspartate in vivo using capillary electrophoresis (CE) with laser-induced …