Purpose Zein/phospholipid composite nanoparticles (CNPs) were developed as a delivery
platform for gallic acid (GA), a polyphenolic compound with reported preclinical antifibrotic …

Hepatic fibrosis (HF) is a chronic hepatic pathological process induced by various liver
injuries, with few available therapies. Previous research studies revealed that HF is …

Purpose Gallic acid (GA) is a polyphenolic compound with proven efficacy against hepatic
fibrosis in experimental animals. However, it suffers from poor bioavailability and rapid …

Hepatocellular carcinoma (HCC) is the most common hepatic malignancy worldwide.
Recent reports focusing on the efficacy of apigenin-loaded nanoparticles (NPs) in combating …

Objectives The aim was to prepare neoglycoprotein-based nanoparticles for targeted drug
delivery to hepatic stellate cells, and to evaluate their characteristics in vitro and in vivo …

Aim Liver fibrosis is mainly characterized by the formation of fibrous scars. Galactosylated
chitosan (GC) has gained increasing attention as a liver-targeted drug carrier in recent …

Liver cancer is one of the most common human malignancies worldwide. Currently,
chemotherapy remains the cornerstone for liver cancer treatment. However, chemotherapy …

Non-alcoholic steatohepatitis (NASH) is the major form of chronic liver disease in adults;
however, there are no approved drugs for NASH. In this study, we designed the PNM-G-PV …

Aim: Lactoferrin (LF)-targeted gliadin nanoparticles (GL-NPs) were developed for targeted
oral therapy of hepatocellular carcinoma. Materials & methods: Celecoxib and diosmin were …

Aim: Tannic acid and vitamin E loaded-poly D, L-lactide-co-glycolic acid (PLGA)
nanoparticles (NP) were developed to achieve hepatoprotection in alcoholic liver disease …