Genetic risk factors in two Utah pedigrees at high risk for suicide
We have used unique population-based data resources to identify 22 high-risk extended
pedigrees that show clustering of suicide over twice that expected from demographically …
pedigrees that show clustering of suicide over twice that expected from demographically …
Genome-wide significant regions in 43 Utah high-risk families implicate multiple genes involved in risk for completed suicide
Suicide is the 10th leading cause of death in the United States. Although environment has
undeniable impact, evidence suggests that genetic factors play a significant role in …
undeniable impact, evidence suggests that genetic factors play a significant role in …
Identifying rare variants for genetic risk through a combined pedigree and phenotype approach: application to suicide and asthma
Suicidal behavior is a complex disorder, with evidence for genetic risk independent of other
genetic risk factors including psychiatric disorders. Since 1996, over 3000 DNA samples …
genetic risk factors including psychiatric disorders. Since 1996, over 3000 DNA samples …
A genome‐wide association study of suicidal behavior
H Galfalvy, F Haghighi, C Hodgkinson… - American Journal of …, 2015 - Wiley Online Library
Genome wide array studies have reported limited success in identifying genetic markers
conferring risk for suicidal behavior (SB). This may be attributable to study designs with …
conferring risk for suicidal behavior (SB). This may be attributable to study designs with …
The genetics of suicide: a critical review of molecular studies
J Brezo, T Klempan, G Turecki - Psychiatric Clinics of North America, 2008 - Elsevier
Genetic epidemiology research has shown that genes contribute to suicide risk.
Unfortunately, the first 30 years of candidate-based association studies have provided little …
Unfortunately, the first 30 years of candidate-based association studies have provided little …
Genomewide association studies of suicide attempts in US soldiers
Suicide is a global public health problem with particular resonance for the US military.
Genetic risk factors for suicidality are of interest as indicators of susceptibility and potential …
Genetic risk factors for suicidality are of interest as indicators of susceptibility and potential …
Genome-wide association study of suicide death and polygenic prediction of clinical antecedents
Objective: Death by suicide is a highly preventable yet growing worldwide health crisis. To
date, there has been a lack of adequately powered genomic studies of suicide, with no …
date, there has been a lack of adequately powered genomic studies of suicide, with no …
[HTML][HTML] Uncommon protein-coding variants associated with suicide attempt in a diverse sample of US Army soldiers
Background Suicide is a societal and public health concern of global scale. Identifying
genetic risk factors for suicide attempt can characterize underlying biology and enable early …
genetic risk factors for suicide attempt can characterize underlying biology and enable early …
Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study
Family studies have shown an aggregation of suicidal behavior in families. Yet, molecular
studies are needed to identify loci accounting for genetic heritability. We conducted a …
studies are needed to identify loci accounting for genetic heritability. We conducted a …
Rare protein‐coding variants implicate genes involved in risk of suicide death
Identification of genetic factors leading to increased risk of suicide death is critical to combat
rising suicide rates, however, only a fraction of the genetic variation influencing risk has …
rising suicide rates, however, only a fraction of the genetic variation influencing risk has …