Resveratrol and exercise combined to treat functional limitations in late life: a pilot randomized controlled trial

SA Harper, JR Bassler, S Peramsetty, Y Yang… - Experimental …, 2021 - Elsevier
Purpose To evaluate the safety and feasibility of combining exercise (EX) and resveratrol to
treat older adults with physical function limitations. Methods Three-arm, two-site pilot …

Resveratrol enhances exercise-induced cellular and functional adaptations of skeletal muscle in older men and women

SE Alway, JL McCrory, K Kearcher… - … Series A: Biomedical …, 2017 - academic.oup.com
Abstract Older men (n= 12) and women (n= 18) 65–80 years of age completed 12 weeks of
exercise and took either a placebo or resveratrol (RSV)(500 mg/d) to test the hypothesis that …

Safety and metabolic outcomes of resveratrol supplementation in older adults: results of a twelve-week, placebo-controlled pilot study

SD Anton, C Embry, M Marsiske, X Lu, H Doss… - Experimental …, 2014 - Elsevier
Resveratrol has been found to have potent antioxidant, anti-inflammatory, and
anticarcinogenic effects. The safety and efficacy of resveratrol supplementation in older …

Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated mice

T Murase, S Haramizu, N Ota, T Hase - Biogerontology, 2009 - Springer
The decline in physical performance with increasing age is a crucial problem in our aging
society. We examined the effects of resveratrol, a natural polyphenolic compound present in …

Resveratrol treatment reduces the appearance of tubular aggregates and improves the resistance to fatigue in aging mice skeletal muscles

L Toniolo, P Fusco, L Formoso, A Mazzi… - Experimental …, 2018 - Elsevier
Resveratrol (RES) is a polyphenolic compound found in grapes, peanuts, and in some
berries. RES has been reported to exhibit antioxidant, anti-inflammatory, anti-proliferative …

Resveratrol primes the effects of physical activity in old mice

E Rodríguez-Bies, BT Tung, P Navas… - British Journal of …, 2016 - cambridge.org
Decrease in muscle mass and performance with ageing is one of the main factors of frailty in
the elderly. Maintenance of muscle performance by involving in physical activities is …

Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice

JR Jackson, MJ Ryan, SE Alway - Journals of Gerontology …, 2011 - academic.oup.com
This study analyzed the capacity of resveratrol, a naturally occurring polyphenol, to reduce
aging-induced oxidative stress and protect against sarcopenia. Middle-aged (18 months) …

[HTML][HTML] A healthier approach to clinical trials evaluating resveratrol for primary prevention of age-related diseases in healthy populations

JM Smoliga, ES Colombo, MJ Campen - Aging (Albany NY), 2013 - ncbi.nlm.nih.gov
In recent years, the wealth of basic science research supporting resveratrol's potential to
treat, delay, and even prevent age-related chronic diseases has led to a number of human …

Resveratrol and/or exercise training counteract aging-associated decline of physical endurance in aged mice; targeting mitochondrial biogenesis and function

MH Muhammad, MM Allam - The Journal of Physiological Sciences, 2018 - Springer
Mitochondrial dysfunction and decreased mitochondrial content are hallmarks of aging that
leads to decreased physical endurance. Our aim was to explore the anti-aging effect of …

Effects of 90 days of resveratrol supplementation on cognitive function in elders: a pilot study

SD Anton, N Ebner, JM Dzierzewski… - The Journal of …, 2018 - liebertpub.com
Objective: The purpose of this trial was to study the effects of chronic resveratrol use on
cognitive function in humans. Design: The authors conducted a double-blind, Phase IIa …