Chitosan–gelatin biopolymers as carrier substrata for limbal epithelial stem cells

A De La Mata, T Nieto-Miguel… - Journal of Materials …, 2013 - Springer
The aim of this work was to evaluate semi-synthetic biopolymers based on chitosan (CH)
and gelatin (G) as potential in vitro carrier substrata for human limbal epithelial cells …

Chitosan-coated alginate membranes for cultivation of limbal epithelial cells to use in the restoration of damaged corneal surfaces

E Öztürk, MA Ergün, Z ÖZtüRk… - … journal of artificial …, 2006 - journals.sagepub.com
Some chemicals or thermal burns may result in abnormal reepithelialization by conjunctival
epithelial cells and it causes different types of damage on the cornea surface. When …

Tissue-engineered scaffold based on carboxymethyl chitin or chitosan for corneal epithelial transplantation

T Li, Y Liang, Z Wang, W Zhang, L Wang, Q Zhou… - Polymer Journal, 2018 - nature.com
Blend membranes based on polysaccharides are used in tissue engineering. In this study,
six groups of blend membranes were prepared with carboxymethyl chitosan (CMCTS) or …

Cellular response of limbal stem cells on PHBV/gelatin nanofibrous scaffold for ocular epithelial regeneration

A Baradaran-Rafii, E Biazar… - International Journal of …, 2015 - Taylor & Francis
The aim of this study was to develop a blend of nanofibrous poly (3-hydroxybutyrate-co-3-
hydroxyvalerate)(PHBV)/gelatin substrate for limbal stem cell (LSC) expansion that can …

Hydrogel membranes based on genipin-cross-linked chitosan blends for corneal epithelium tissue engineering

M Grolik, K Szczubiałka, B Wowra… - Journal of Materials …, 2012 - Springer
Novel polymeric hydrogel scaffolds for corneal epithelium cell culturing based on blends of
chitosan with some other biopolymers such as hydroxypropylcellulose, collagen and elastin …

Simplifying corneal surface regeneration using a biodegradable synthetic membrane and limbal tissue explants

P Deshpande, C Ramachandran, F Sefat, I Mariappan… - Biomaterials, 2013 - Elsevier
Currently, damage to the ocular surface can be repaired by transferring laboratory cultured
limbal epithelial cells (LECs) to the cornea using donor human amniotic membrane as the …

A biomimetic scaffold for culturing limbal stem cells: a promising alternative for clinical transplantation

S Dravida, S Gaddipati, M Griffith… - Journal of tissue …, 2008 - Wiley Online Library
Limbal tissues can be cultured on various types of scaffolds to create a sheet of limbal‐
corneal epithelium for research as well as clinical transplantation. An optically clear …

Comparison between different biomaterial scaffolds for limbal-derived stem cells growth and enrichment

MF Forni, RR Loureiro, PC Cristovam… - Current eye …, 2013 - Taylor & Francis
Purpose/Aim: Corneal epithelial stem cells have been used for the treatment of total limbal
deficiency with corneal conjunctivalization and decreased vision secondary to a variety of …

Plasma polymer-coated contact lenses for the culture and transfer of corneal epithelial cells in the treatment of limbal stem cell deficiency

KD Brown, S Low, I Mariappan, KM Abberton… - … engineering part A, 2014 - liebertpub.com
Extensive damage to the limbal region of the cornea leads to a severe form of corneal
blindness termed as limbal stem cell deficiency (LSCD). Whereas most cases of corneal …

Fabrication and characters of a corneal endothelial cells scaffold based on chitosan

Y Liang, W Liu, B Han, C Yang, Q Ma, W Zhao… - Journal of Materials …, 2011 - Springer
A novel chitosan-based membrane that made of hydroxyethyl chitosan, gelatin and
chondroitin sulfate was used as a carrier of corneal endothelial cells. The characteristics of …