Melting temperatures, T m, were systematically studied for a set of 92 DNA duplex oligomers
in a variety of sodium ion concentrations ranging from 69 mM to 1.02 M. The relationship …

Accurate predictions of DNA stability in physiological and enzyme buffers are important for
the design of many biological and biochemical assays. We therefore investigated the effects …

Many important applications of DNA sequence‐dependent hybridization reactions have
recently emerged. This has sparked a renewed interest in analytical calculations of …

Melting temperature, Tm, is an important property of nucleic acid duplexes. It is typically
determined from spectroscopic or calorimetric melting experiments. More than one analytical …

A clear difference in the enthalpy changes derived from spectroscopic and calorimetric
measurements has recently been shown. The exact interpretation of this deviation varied …

Thermodynamic data were determined from UV absorbance vs temperature profiles of 23
oligonucleotides. These data were combined with data from the literature for 21 sequences …

Thermodynamics of the thermal dissociation transitions of 10 bp PNA/DNA duplexes and
their corresponding DNA/DNA duplexes in 10 mM sodium phosphate buffer (pH 7.0) were …

The design of modified nucleic acid probes, primers, and therapeutics is improved by
considering their thermodynamics. Locked nucleic acid (LNA) is one of the most useful …

The use of short oligonucleotide probes is finding increased application in DNA sequencing
and genome characterization techniques, but a lack of knowledge of the hybridization …

The stability of DNA duplex and triplex structures not only depends on molecular forces such
as base pairing or tripling or electrostatic interactions but also is sensitive to its aqueous …