Although fibrotic disorders are frequently assumed to be linked to T H2 cells, quantitative
tissue interrogation studies have rarely been performed to establish this link and certainly …

Fibrosing mediastinitis (FM) and IgG4‐related disease (IgG4‐RD) are two fibroinflammatory
disorders with potentially overlapping clinical and radiological features. In this paper, we …

Background Fibrosing mediastinitis (FM) is an idiosyncratic reaction to infection with
Histoplasma capsulatum with a prevalence of 3: 100,000 people infected. The rarity of post …

Fibrosing mediastinitis is characterized by abnormal proliferation of acellular collagen and
fibrous tissue in the mediastinum. Although most cases in the United States are attributed to …

Fibrosing mediastinitis (FM) is a rare disorder characterized by the invasive proliferation of
fibrous tissue within the mediastinum. FM frequently results in the compression of vital …

Fibrosing mediastinitis is an uncommon disorder characterized by inflammation and
progressive fibrosis within the mediastinum (1–3). The resulting invasive obstruction of vital …

Fibrosis is an important health problem and its pathogenetic activation is still largely
unknown. It can develop either spontaneously or, more frequently, as a consequence of …

Background How T follicular (Tfh) cells contribute to many different B-cell class-switching
events during T-cell–dependent immune responses has been unclear. Diseases with …

Systemic sclerosis (SSc) is a connective tissue disease characterized by progressive fibrosis
of the skin and internal organs. SSc is an immunologically mediated disease. A prominent …

Abstract IgG4-related disease (IgG4-RD) is a new disease entity characterized by type 2
helper T (Th2)-dominant inflammation and progressive fibrosis. We found the infiltration of …