Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease that probably
involves several genetic loci. Several rare genetic variants and one common single …
involves several genetic loci. Several rare genetic variants and one common single …
Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study
Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with
high mortality, uncertain cause, and few treatment options. Studies have identified a …
high mortality, uncertain cause, and few treatment options. Studies have identified a …
Association between the MUC5B promoter polymorphism and survival in patients with idiopathic pulmonary fibrosis
AL Peljto, Y Zhang, TE Fingerlin, SF Ma, JGN Garcia… - Jama, 2013 - jamanetwork.com
Importance Current prediction models of mortality in idiopathic pulmonary fibrosis (IPF),
which are based on clinical and physiological parameters, have modest value in predicting …
which are based on clinical and physiological parameters, have modest value in predicting …
[PDF][PDF] Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics
The research of rare and devastating orphan diseases, such as idiopathic pulmonary
fibrosis (IPF) has been limited by the rarity of the disease itself. The prognosis is poor—the …
fibrosis (IPF) has been limited by the rarity of the disease itself. The prognosis is poor—the …
Pulmonary fibrosis in the era of stratified medicine
SK Mathai, CA Newton, DA Schwartz, CK Garcia - Thorax, 2016 - thorax.bmj.com
Both common and rare variants contribute to the genetic architecture of pulmonary fibrosis.
Genome-wide association studies have identified common variants, or those with a minor …
Genome-wide association studies have identified common variants, or those with a minor …
Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis
Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterized by
scarring of the lung that is believed to result from an atypical response to injury of the …
scarring of the lung that is believed to result from an atypical response to injury of the …
The MUC5B promoter polymorphism is associated with idiopathic pulmonary fibrosis in a Mexican cohort but is rare among Asian ancestries
AL Peljto, M Selman, DS Kim, E Murphy, L Tucker… - Chest, 2015 - Elsevier
BACKGROUND Polymorphisms in the MUC5B promoter, TOLLIP, and nine additional
genetic loci have been associated with idiopathic pulmonary fibrosis (IPF) within non …
genetic loci have been associated with idiopathic pulmonary fibrosis (IPF) within non …
Overlap of genetic risk between interstitial lung abnormalities and idiopathic pulmonary fibrosis
Rationale: Interstitial lung abnormalities (ILAs) are associated with the highest genetic risk
locus for idiopathic pulmonary fibrosis (IPF); however, the extent to which there are unique …
locus for idiopathic pulmonary fibrosis (IPF); however, the extent to which there are unique …
Genetic risk factors for idiopathic pulmonary fibrosis: insights into immunopathogenesis
JE Michalski, DA Schwartz - Journal of Inflammation Research, 2021 - Taylor & Francis
Idiopathic pulmonary fibrosis is an etiologically complex interstitial lung disease
characterized by progressive scarring of the lungs with a subsequent decline in lung …
characterized by progressive scarring of the lungs with a subsequent decline in lung …
An exome sequencing study to assess the role of rare genetic variation in pulmonary fibrosis
Rationale: Idiopathic pulmonary fibrosis (IPF) is an increasingly recognized, often fatal lung
disease of unknown etiology. Objectives: The aim of this study was to use whole-exome …
disease of unknown etiology. Objectives: The aim of this study was to use whole-exome …