Acute toxicological effects of copper nanoparticles in vivo

Z Chen, H Meng, G Xing, C Chen, Y Zhao, G Jia… - Toxicology letters, 2006 - Elsevier
To assess the toxicity of copper nanoparticles (23.5 nm) in vivo, LD50, morphological
changes, pathological examinations and blood biochemical indexes of experimental mice …

Acute toxicity and biodistribution of different sized copper nano-particles in rats after oral administration

H Tang, M Xu, XR Zhou, Y Zhang, L Zhao, G Ye… - Materials Science and …, 2018 - Elsevier
In order to compare the detailed toxicity of nano‑copper and CuCl 2· 2H 2 O (Cu ions) in
vivo, the oral toxicity of four differently sized Cu particles (30 nm, 50 nm, 80 nm and 1 μm) on …

Comparative toxicity and biodistribution of copper nanoparticles and cupric ions in rats

IC Lee, JW Ko, SH Park, JO Lim, IS Shin… - International journal …, 2016 - Taylor & Francis
Despite widespread use and prospective biomedical applications of copper nanoparticles
(Cu NPs), their biosafety issues and kinetics remain unclear. Thus, the aim of this study was …

Ultrahigh reactivity provokes nanotoxicity: explanation of oral toxicity of nano-copper particles

H Meng, Z Chen, G Xing, H Yuan, C Chen, F Zhao… - Toxicology letters, 2007 - Elsevier
Recently, studies on the biological effects of nanomaterials show signs that some of the
manufactured nanoparticles exhibit unexpected toxicity to living organisms. It has previously …

[HTML][HTML] Toxicity of manufactured copper nanoparticles-A review

M Hejazy, MK Koohi… - Nanomedicine …, 2018 - nanomedicine-rj.com
The health effects of nanoparticles (NPs) are raising considerable and growing concerns
from the public and government around the world. Nano-metals are new forms of metal with …

Comparative toxicological effects of biologically and chemically synthesized copper oxide nanoparticles on mice

BE El Bialy, RA Hamouda, MA Abd Eldaim… - International journal …, 2020 - Taylor & Francis
Introduction Copper oxide nanoparticles (CuO-NPs) are widely used as feed additives for
livestock and poultry and implicated in many biomedical applications; however, overload of …

Size-dependent toxicity of metal oxide particles—a comparison between nano-and micrometer size

HL Karlsson, J Gustafsson, P Cronholm, L Möller - Toxicology letters, 2009 - Elsevier
Toxicological studies have shown increased toxicity of nanoparticles (< 100nm) compared to
micrometer particles of the same composition, which has raised concern about the impact on …

Nanoparticle cytotoxicity depends on intracellular solubility: comparison of stabilized copper metal and degradable copper oxide nanoparticles

AM Studer, LK Limbach, L Van Duc, F Krumeich… - Toxicology letters, 2010 - Elsevier
Metal nanoparticles have distinctly different chemical and physical properties than currently
investigated oxides. Since pure metallic nanoparticles are igniting at air, carbon stabilized …

Acute and subacute oral toxicity of copper oxide nanoparticles in female albino Wistar rats

LSP Bugata, P Pitta Venkata, AR Gundu… - Journal of Applied …, 2019 - Wiley Online Library
The extensive use of copper oxide nanoparticles (CuO‐NPs) in various industries and their
wide range of applications have led to their accumulation in different ecological niches of the …

In vitro intestinal toxicity of copper oxide nanoparticles in rat and human cell models

TE Henson, J Navratilova, AH Tennant… - …, 2019 - Taylor & Francis
Human oral exposure to copper oxide nanoparticles (NPs) may occur following ingestion,
hand-to-mouth activity, or mucociliary transport following inhalation. This study assessed the …