Assay of plasma phosphorylated tau protein (threonine 181) and total tau protein in early-stage Alzheimer's disease
CC Yang, MJ Chiu, TF Chen, HL Chang… - Journal of …, 2018 - content.iospress.com
The feasibility of assaying plasma phosphorylated tau protein (threonine 181), denoted p-
tau181, using immunomagnetic reduction (IMR) is explored. The reagent for assaying p …
tau181, using immunomagnetic reduction (IMR) is explored. The reagent for assaying p …
Levels of total tau and tau protein phosphorylated at threonine 181 in patients with incipient and manifest Alzheimer's disease
P Schönknecht, J Pantel, A Hunt, M Volkmann… - Neuroscience …, 2003 - Elsevier
Cerebrospinal fluid tau protein levels are considered to be a promising marker for
Alzheimer's disease (AD) and may facilitate early detection. Using the newly developed …
Alzheimer's disease (AD) and may facilitate early detection. Using the newly developed …
Differences between plasma and cerebrospinal fluid p-tau181 and p-tau231 in early Alzheimer's disease
A Pilotto, M Parigi, G Bonzi, B Battaglio… - Journal of …, 2022 - content.iospress.com
Plasma phosphorylated tau species have been recently proposed as peripheral markers of
Alzheimer's disease (AD) pathology. In this cross-sectional study including 91 subjects …
Alzheimer's disease (AD) pathology. In this cross-sectional study including 91 subjects …
Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease …
Background There is still a substantial unmet need for less invasive and lower-cost blood-
based biomarkers to detect brain Alzheimer's disease (AD) pathology. This study is aimed to …
based biomarkers to detect brain Alzheimer's disease (AD) pathology. This study is aimed to …
Estimation of Tau and Phosphorylated Tau181 in Serum of Alzheimer's Disease and Mild Cognitive Impairment Patients
The elevated level of cerebrospinal fluid (CSF) Tau and phosphorylated Tau181 (p-Tau181)
proteins are well established hallmarks of Alzheimer's disease (AD). Elevated level of p …
proteins are well established hallmarks of Alzheimer's disease (AD). Elevated level of p …
The presence of select tau species in human peripheral tissues and their relation to Alzheimer's disease
BN Dugger, CM Whiteside, CL Maarouf… - Journal of …, 2016 - content.iospress.com
Tau becomes excessively phosphorylated in Alzheimer's disease (AD) and is widely studied
within the brain. Further examination of the extent and types of tau present in peripheral …
within the brain. Further examination of the extent and types of tau present in peripheral …
Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231
K Buerger, R Zinkowski, SJ Teipel, T Tapiola… - Archives of …, 2002 - jamanetwork.com
Background Phosphorylation of tau protein at threonine 231 (using full-length tau, 441
amino acids, for the numbering scheme)(p-tau 231) occurs specifically in postmortem brain …
amino acids, for the numbering scheme)(p-tau 231) occurs specifically in postmortem brain …
Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer's disease: original data and review of the literature
P Lewczuk, H Esselmann, M Bibl, G Beck… - Journal of Molecular …, 2004 - Springer
Cerebrospinal fluid (CSF) concentrations of total Tau and Tau phosphorylated at threonine
(position 181 [pTau181]) were studied with ELISA in a group of carefully selected patients …
(position 181 [pTau181]) were studied with ELISA in a group of carefully selected patients …
Isoelectric point differentiates PHF-tau from biopsy-derived human brain tau proteins
N Sergeant, T Bussiere, P Vermersch, JP Lejeune… - …, 1995 - journals.lww.com
IN the present study, Tau proteins were detected by two monoclonal antibodies AD2 and
Tau-1 raised against PHF-tau and normal Tau proteins respectively using single-and two …
Tau-1 raised against PHF-tau and normal Tau proteins respectively using single-and two …
Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease
H Hampel, K Bürger, JC Pruessner… - Archives of …, 2005 - jamanetwork.com
Background The microtubule-associated tau protein abnormally phosphorylated at
threonine 231 (p-tau 231) has been investigated as a potential marker of Alzheimer disease …
threonine 231 (p-tau 231) has been investigated as a potential marker of Alzheimer disease …
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