The feasibility of assaying plasma phosphorylated tau protein (threonine 181), denoted p-
tau181, using immunomagnetic reduction (IMR) is explored. The reagent for assaying p …

Cerebrospinal fluid tau protein levels are considered to be a promising marker for
Alzheimer's disease (AD) and may facilitate early detection. Using the newly developed …

Plasma phosphorylated tau species have been recently proposed as peripheral markers of
Alzheimer's disease (AD) pathology. In this cross-sectional study including 91 subjects …

Background There is still a substantial unmet need for less invasive and lower-cost blood-
based biomarkers to detect brain Alzheimer's disease (AD) pathology. This study is aimed to …

The elevated level of cerebrospinal fluid (CSF) Tau and phosphorylated Tau181 (p-Tau181)
proteins are well established hallmarks of Alzheimer's disease (AD). Elevated level of p …

Tau becomes excessively phosphorylated in Alzheimer's disease (AD) and is widely studied
within the brain. Further examination of the extent and types of tau present in peripheral …

Background Phosphorylation of tau protein at threonine 231 (using full-length tau, 441
amino acids, for the numbering scheme)(p-tau 231) occurs specifically in postmortem brain …

Cerebrospinal fluid (CSF) concentrations of total Tau and Tau phosphorylated at threonine
(position 181 [pTau181]) were studied with ELISA in a group of carefully selected patients …

IN the present study, Tau proteins were detected by two monoclonal antibodies AD2 and
Tau-1 raised against PHF-tau and normal Tau proteins respectively using single-and two …

Background The microtubule-associated tau protein abnormally phosphorylated at
threonine 231 (p-tau 231) has been investigated as a potential marker of Alzheimer disease …