An infant with a family history of congenital alveolar proteinosis associated with surfactant
protein B (SP-B) deficiency was identified when SP-B was not detected in amniotic fluid …

Objective. To evaluate components of pulmonary surfactant and identify mutations in the
surfactant protein B gene (SP-B) of a term infant with severe respiratory distress and chronic …

A 38-day-old male infant with persistent pulmonary hypertension and respiratory failure
since birth was found to have a complete absence of surfactant protein B (SP-B) along with …

Congenital alveolar proteinosis due to surfactant protein B deficiency is an inherited disease
which results in severe respiratory failure in term infants soon after birth. The …

To determine the molecular defect accounting for the deficiency of pulmonary surfactant
protein B (SP-B) in full-term neonates who died from respiratory failure associated with …

Congenital alveolar proteinosis and misalignment of lung vessels are rare disorders. We
report on five infants of consanguineous kindred. All infants were delivered at term after …

Congenital alveolar proteinosis (CAP), a cause of respiratory failure in fill-term newborns,
often leads to death in infancy despite medical therapy. We recently described an inherited …

Hereditary surfactant protein B (SP-B) deficiency causes lethal neonatal respiratory disease
associated with abnormalities in pulmonary surfactant proteins and lipids. SP-C, a 4-kDa …

Abstract Surfactant Protein B (SP-B) deficiency has been recently identified as an
uncommon, autosomal recessive lung disorder in term infants. This inability to produce SP-B …

Hereditary surfactant protein B (SP-B) deficiency is an autosomal recessive disease in which
affected infants are unable to produce normally functional surfactant, resulting in neonatal …