[HTML][HTML] Second-generation antipsychotics and metabolism alterations: a systematic review of the role of the gut microbiome
K Skonieczna-Żydecka, I Łoniewski, A Misera… - …, 2019 - Springer
Rationale Multiple drugs are known to induce metabolic malfunctions, among them second-
generation antipsychotics (SGAs). The pathogenesis of such adverse effects is of …
generation antipsychotics (SGAs). The pathogenesis of such adverse effects is of …
[HTML][HTML] Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat
KJ Davey, PD Cotter, O O'sullivan, F Crispie… - Translational …, 2013 - nature.com
The atypical antipsychotic olanzapine is often associated with serious metabolic side effects
including weight gain and increased visceral fat. These adverse events are a considerable …
including weight gain and increased visceral fat. These adverse events are a considerable …
[HTML][HTML] Use of the second-generation antipsychotic, risperidone, and secondary weight gain are associated with an altered gut microbiota in children
SM Bahr, BC Tyler, N Wooldridge, BD Butcher… - Translational …, 2015 - nature.com
The atypical antipsychotic risperidone (RSP) is often associated with weight gain and
cardiometabolic side effects. The mechanisms for these adverse events are poorly …
cardiometabolic side effects. The mechanisms for these adverse events are poorly …
Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters
KJ Davey, SM O'Mahony, H Schellekens… - …, 2012 - Springer
Abstract Rationale Atypical antipsychotic drugs (AAPDs) such as olanzapine have a serious
side effect profile including weight gain and metabolic dysfunction, and a number of studies …
side effect profile including weight gain and metabolic dysfunction, and a number of studies …
[HTML][HTML] The effects of antipsychotic medications on microbiome and weight gain in children and adolescents
Background Atypical antipsychotics, also known as second-generation antipsychotics, are
commonly prescribed as treatment for psychotic disorders in adults, as well as in children …
commonly prescribed as treatment for psychotic disorders in adults, as well as in children …
Antipsychotics-induced metabolic alterations: recounting the mechanistic insights, therapeutic targets and pharmacological alternatives
Atypical antipsychotics (AAPs) are the drug of choice in the management of mental illnesses
by virtue of their advantage over typical antipsychotics ie least tendency of producing …
by virtue of their advantage over typical antipsychotics ie least tendency of producing …
[HTML][HTML] Prebiotic attenuation of olanzapine-induced weight gain in rats: analysis of central and peripheral biomarkers and gut microbiota
ACC Kao, S Spitzer, DC Anthony, B Lennox… - Translational …, 2018 - nature.com
Olanzapine is an effective antipsychotic drug but since it causes significant weight gain, it is
not well tolerated by psychosis patients. The prebiotic, B-GOS®, attenuates metabolic …
not well tolerated by psychosis patients. The prebiotic, B-GOS®, attenuates metabolic …
The microbiome-gut-brain axis: implications for schizophrenia and antipsychotic induced weight gain
S Kanji, TM Fonseka, VS Marshe… - European archives of …, 2018 - Springer
With the emergence of knowledge implicating the human gut microbiome in the
development and regulation of several physiological systems, evidence has accumulated to …
development and regulation of several physiological systems, evidence has accumulated to …
[HTML][HTML] The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse
AP Morgan, JJ Crowley, RJ Nonneman… - PloS one, 2014 - journals.plos.org
The second-generation antipsychotic olanzapine is effective in reducing psychotic
symptoms but can cause extreme weight gain in human patients. We investigated the role of …
symptoms but can cause extreme weight gain in human patients. We investigated the role of …
Gut microbiome in schizophrenia and antipsychotic-induced metabolic alterations: A scoping review
R Singh, N Stogios, E Smith, J Lee… - Therapeutic …, 2022 - journals.sagepub.com
Schizophrenia (SCZ) is a severe mental disorder with high morbidity and lifetime disability
rates. Patients with SCZ have a higher risk of developing metabolic comorbidities such as …
rates. Patients with SCZ have a higher risk of developing metabolic comorbidities such as …