[HTML][HTML] Lipidomic analysis of cells and extracellular vesicles from high-and low-metastatic triple-negative breast cancer

N Nishida-Aoki, Y Izumi, H Takeda, M Takahashi… - Metabolites, 2020 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer nanovesicles secreted from almost all cells
including cancer. Cancer-derived EVs contribute to cancer progression and malignancy via …

Discovery of lipid profiles in plasma‐derived extracellular vesicles as biomarkers for breast cancer diagnosis

L Liu, M Kawashima, M Sugimoto, K Sonomura… - Cancer …, 2023 - Wiley Online Library
Lipids are a major component of extracellular vesicles; however, their significance in
tumorigenesis and progression has not been well elucidated. As we previously found that …

Extracellular vesicles as a promising source of lipid biomarkers for breast cancer detection in blood plasma

E Dorado, ML Doria, A Nagelkerke… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), including exosomes and microvesicles, mediate intercellular
communication in cancer, from development to metastasis. EV‐based liquid biopsy is a …

Extracellular vesicles as biomarkers and therapeutic targets in breast cancer

L Sadovska, J Eglītis, A Linē - Anticancer research, 2015 - ar.iiarjournals.org
Cancer-derived extracellular vesicles (EVs) contain various cancer-associated molecules,
such as mutated or overexpressed oncoproteins, glycoproteins, mRNAs, various non-coding …

[HTML][HTML] Lipid raft integrity is required for survival of triple negative breast cancer cells

A Badana, M Chintala, G Varikuti… - Journal of breast …, 2016 - synapse.koreamed.org
Purpose Lipid rafts are cholesterol enriched microdomains that colocalize signaling
pathways involved in cell proliferation, metastasis, and angiogenesis. We examined the …

[HTML][HTML] Extracellular vesicles in the treatment and diagnosis of breast cancer: a status update

X Zhang, C Wang, J Yu, J Bu, F Ai, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Breast cancer is one of the leading causes of cancer-related death in women. Currently, the
treatment of breast cancer is limited by the lack of effectively targeted therapy and patients …

[HTML][HTML] Extracellular vesicles: the landscape in the progression, diagnosis, and treatment of triple-negative breast cancer

M Dong, Q Liu, Y Xu, Q Zhang - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a heterogeneous subtype of breast cancer (BC) with
diverse biological behavior, high aggressiveness, and poor prognosis. Extracellular vesicles …

Roles of extracellular vesicles in metastatic breast cancer

J Peng, W Wang, S Hua, L Liu - Breast cancer: basic and …, 2018 - journals.sagepub.com
Cells can secrete extracellular vesicles (EVs) to communicate with neighboring or distant
cells by EVs which are composed of a lipid bilayer containing transmembrane proteins and …

[HTML][HTML] Extracellular vesicles from young women's breast cancer patients drive increased invasion of non-malignant cells via the Focal Adhesion Kinase pathway: A …

KR Jordan, JK Hall, T Schedin, M Borakove… - Breast Cancer …, 2020 - Springer
Abstract Background Extracellular vesicles (EVs) are small membrane particles that
contribute to cancer progression and metastases by transporting biologically significant …

[HTML][HTML] Extracellular vesicles as mediators of cell-cell communication in ovarian cancer and beyond–A lipids focus

S Rani, A Lai, S Nair, S Sharma, A Handberg… - Cytokine & growth factor …, 2023 - Elsevier
Extracellular vesicles (EVs) are messengers that carry information in the form of proteins,
lipids, and nucleic acids and are not only essential for intercellular communication but also …