Health effects of phloretin: from chemistry to medicine

S Behzad, A Sureda, D Barreca, SF Nabavi… - Phytochemistry …, 2017 - Springer
Dihydrochalcones are a class of secondary metabolites, whose demand in biological and
pharmacological applications is rapidly growing. Phloretin is one of the best known and …

[HTML][HTML] Biochemical basis of anti-cancer-effects of phloretin—A natural dihydrochalcone

BY Choi - Molecules, 2019 - mdpi.com
Apple is a rich source of bioactive phytochemicals that help improve health by preventing
and/or curing many disease processes, including cancer. One of the apple polyphenols is …

Pharmacological aspects and potential use of phloretin: A systemic review

AVA Mariadoss, R Vinyagam… - Mini reviews in …, 2019 - ingentaconnect.com
Over the past two decades, many researchers have concluded that a diet rich in
polyphenolic compounds plays an important therapeutic role in reducing the risk of cancer …

Phloretin‐induced cytoprotective effects on mammalian cells: A mechanistic view and future directions

MR de Oliveira - Biofactors, 2016 - Wiley Online Library
Abstract Phloretin (C15H14O5), a dihydrochalcone flavonoid, is mainly found in fruit, leaves,
and roots of apple tree. Phloretin exerts antioxidant, anti‐inflammatory, and anti‐tumor …

[HTML][HTML] Phloretin, as a potent anticancer compound: from chemistry to cellular interactions

HS Tuli, P Rath, A Chauhan, S Ramniwas, K Vashishth… - Molecules, 2022 - mdpi.com
Phloretin is a natural dihydrochalcone found in many fruits and vegetables, especially in
apple tree leaves and the Manchurian apricots, exhibiting several therapeutic properties …

[HTML][HTML] Therapeutic potential and pharmaceutical development of a multitargeted flavonoid phloretin

KT Nakhate, H Badwaik, R Choudhary, K Sakure… - Nutrients, 2022 - mdpi.com
Phloretin is a flavonoid of the dihydrogen chalcone class, present abundantly in apples and
strawberries. The beneficial effects of phloretin are mainly associated with its potent …

Importance of thymoquinone, sulforaphane, phloretin, and epigallocatechin and their health benefits

MH Shahrajabian, W Sun - Letters in Drug Design & Discovery, 2024 - ingentaconnect.com
Natural products have a broad diversity of multidimensional chemical formations, which play
an important role, and indicate the crucial nature as a golden source for gaining herbal drug …

[HTML][HTML] Dihydrochalcones: Methods of acquisition and pharmacological properties—A first systematic review

M Stompor, D Broda, A Bajek-Bil - Molecules, 2019 - mdpi.com
Dihydrochalcones are a class of secondary metabolites, for which demand in biological and
pharmacological applications is still growing. They posses several health-endorsing …

Dermatological applications of the flavonoid phloretin

TPA Casarini, LA Frank, AR Pohlmann… - European journal of …, 2020 - Elsevier
Botanical molecules are known to have the ability to counteract ultraviolet radiation-induced
skin damage. The interest in the development of natural compound-based products for the …

[HTML][HTML] Studies on pharmacokinetic properties and absorption mechanism of phloretin: In vivo and in vitro

Y yuan Zhao, Y Fan, M Wang, J Wang… - Biomedicine & …, 2020 - Elsevier
Phloretin is a natural dihydrochalcone flavonoid that is mainly distributed in apple, pear and
other juicy fruit peels or root peels. Phloretin exhibits several pharmacological properties …