Autoimmune diseases affect approximately 5% of the population, but much work remains to
define the genetic risk factors and pathogenic mechanisms underlying these conditions …

The aim of this study was to determine whether the functional protein tyrosine phosphatase
nonreceptor 22 (PTPN22) C1858T polymorphism (rs2476601) confers susceptibility to …

Studies performed in the past years showed PTNP22 1858 C> T (rs2476601) polymorphism
as associated with systemic lupus erythematosus susceptibility, although conflicting findings …

To assess the association between PTPN22 1858C> T gene polymorphism and
susceptibility to, and clinical presentation of, systemic lupus erythematosus (SLE). Our study …

Abstract Objective The R620W (1858C→ T) polymorphism in PTPN22 has been implicated
in type 1 diabetes mellitus, rheumatoid arthritis, Graves' disease, Hashimoto thyroiditis …

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-
cell activation associated with several autoimmune diseases, including systemic lupus …

The protein tyrosine phosphatase non-receptor 22 (PTPN22) 1858 C> T poly-morphic
variant gene (rs2476601) displays an association with systemic lupus erythematosus (SLE) …

Abstract Objective The C1858T polymorphism in PTPN22 has been associated with the risk
of systemic lupus erythematosus (SLE) as well as multiple other autoimmune diseases. We …

To assess the possible association between the protein tyrosine phosphatases non-receptor
22 (PTPN22) gene 1858 CT polymorphism and the predisposition to systemic lupus …

Objective Recently, a functional PTPN22 variant (R263Q; rs33996649) was found to be
associated with systemic lupus erythematosus (SLE). This study was undertaken to analyze …