Y‐box protein‐1 is actively secreted through a non‐classical pathway and acts as an extracellular mitogen
BC Frye, S Halfter, S Djudjaj, P Muehlenberg… - EMBO …, 2009 - embopress.org
Y‐box protein (YB)‐1 of the cold‐shock protein family functions in gene transcription and
RNA processing. Extracellular functions have not been reported, but the YB‐1 staining …
RNA processing. Extracellular functions have not been reported, but the YB‐1 staining …
[HTML][HTML] Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1
A Bernhardt, A Fehr, S Brandt, S Jerchel… - Kidney international, 2017 - Elsevier
Tubular cells recruit monocytic cells in inflammatory tubulointerstitial kidney diseases. The
cell-cell communication that establishes pro-or anti-inflammatory activities is mainly …
cell-cell communication that establishes pro-or anti-inflammatory activities is mainly …
YB-1 is an early and central mediator of bacterial and sterile inflammation in vivo
L Hanssen, C Alidousty, S Djudjaj, BC Frye… - The Journal of …, 2013 - journals.aai.org
In vitro studies identified Y-box–binding protein (YB)-1 as a key regulator of inflammatory
mediators. In this study, we observed increased levels of secreted YB-1 in sera from sepsis …
mediators. In this study, we observed increased levels of secreted YB-1 in sera from sepsis …
Oxidative stress causes enhanced secretion of YB-1 protein that restrains proliferation of receiving cells
The prototype cold-shock Y-box binding protein 1 (YB-1) is a multifunctional protein that
regulates a variety of fundamental biological processes including cell proliferation and …
regulates a variety of fundamental biological processes including cell proliferation and …
Role of cold shock Y-box protein-1 in inflammation, atherosclerosis and organ transplant rejection
Chemokines (chemoattractant cytokines) are crucial regulators of immune cell extravasation
from the bloodstream into inflamed tissue. Dysfunctional regulation and perpetuated …
from the bloodstream into inflamed tissue. Dysfunctional regulation and perpetuated …
Cold shock proteins: from cellular mechanisms to pathophysiology and disease
JA Lindquist, PR Mertens - Cell Communication and Signaling, 2018 - Springer
Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the
presence of one or more cold shock domains. In humans, the best characterized members of …
presence of one or more cold shock domains. In humans, the best characterized members of …
Cold shock Y-box protein-1 participates in signaling circuits with auto-regulatory activities
S Brandt, U Raffetseder, S Djudjaj, A Schreiter… - European journal of cell …, 2012 - Elsevier
The cold shock protein Y-box (YB) binding-1 is an example of a highly regulated protein with
pleiotropic functions. Besides activities as a transcription factor in the nucleus or regulator of …
pleiotropic functions. Besides activities as a transcription factor in the nucleus or regulator of …
YB-1: oncoprotein, prognostic marker and therapeutic target?
Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …
changes required for the development and persistence of tumours [Hanahan and Weinberg …
Targeted disruption of one allele of the Y-box protein gene, Chk-YB-1b, in DT40 cells results in major defects in cell cycle
SK Swamynathan, BR Varma, KT Weber… - … and biophysical research …, 2002 - Elsevier
Y-box or inverted CCAAT box-binding proteins are multifunctional regulators of transcription
and translation of several genes. Although YB-1 has been shown to play a key role in cell …
and translation of several genes. Although YB-1 has been shown to play a key role in cell …
Y‐box binding protein‐1 is a novel molecular target for tumor vessels
M Takahashi, S Shimajiri, H Izumi, G Hirano… - Cancer …, 2010 - Wiley Online Library
Y‐box binding protein‐1 (YB‐1) is a member of the cold shock protein family and functions
in transcription and translation. Many reports indicate that YB‐1 is highly expressed in tumor …
in transcription and translation. Many reports indicate that YB‐1 is highly expressed in tumor …