The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway

MH Viegas, NH Gehring, S Breit… - Nucleic acids …, 2007 - academic.oup.com
Nonsense-mediated mRNA decay (NMD) is a molecular pathway of mRNA surveillance that
ensures rapid degradation of mRNAs containing premature translation termination codons …

No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors

J Mailliot, M Vivoli-Vega, C Schaffitzel - Biochemical Journal, 2022 - portlandpress.com
Nonsense-mediated messenger RNA decay (NMD) represents one of the main surveillance
pathways used by eukaryotic cells to control the quality and abundance of mRNAs and to …

Regulation of nonsense-mediated mRNA decay: implications for physiology and disease

R Karam, J Wengrod, LB Gardner… - Biochimica et Biophysica …, 2013 - Elsevier
Nonsense-mediated mRNA decay (NMD) is an mRNA quality control mechanism that
destabilizes aberrant mRNAs harboring premature termination (nonsense) codons (PTCs) …

[HTML][HTML] mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons

I Behm-Ansmant, I Kashima, J Rehwinkel, J Saulière… - FEBS letters, 2007 - Elsevier
Nonsense-mediated mRNA decay (NMD) is an mRNA surveillance pathway which ensures
the rapid degradation of mRNAs containing premature translation termination codons (PTCs …

[HTML][HTML] Nonsense-mediated mRNA decay, a simplified view of a complex mechanism

J Carrard, F Lejeune - BMB reports, 2023 - ncbi.nlm.nih.gov
Nonsense-mediated mRNA decay (NMD) is both a quality control mechanism and a gene
regulation pathway. It has been studied for more than 30 years, with an accumulation of …

Analysis of nonsense‐mediated mRNA decay in mammalian cells

P Nicholson, R Joncourt… - Current Protocols in Cell …, 2012 - Wiley Online Library
The nonsense‐mediated mRNA decay (NMD) pathway acts to selectively identify and
degrade mRNAs that contain a premature translation termination codon (PTC), and hence …

Identification and characterization of novel factors that act in the nonsense‐mediated mRNA decay pathway in nematodes, flies and mammals

A Casadio, D Longman, N Hug, L Delavaine… - EMBO …, 2015 - embopress.org
Nonsense‐mediated mRNA decay (NMD) is a surveillance mechanism that degrades
mRNA s harboring premature termination codons (PTCs). We have conducted a genome …

[HTML][HTML] The mammalian nonsense-mediated mRNA decay pathway: to decay or not to decay! Which players make the decision?

AL Silva, L Romão - FEBS letters, 2009 - Elsevier
Nonsense-mediated mRNA decay (NMD) degrades mRNAs carrying premature translation
termination codons (PTCs). Although the core process and several NMD effectors are …

Control of gene expression through the nonsense-mediated RNA decay pathway

A Nickless, JM Bailis, Z You - Cell & bioscience, 2017 - Springer
Nonsense-mediated RNA decay (NMD) was originally discovered as a cellular surveillance
pathway that safeguards the quality of mRNA transcripts in eukaryotic cells. In its canonical …

Regulation of nonsense‐mediated mRNA decay

L Huang, MF Wilkinson - Wiley Interdisciplinary Reviews: RNA, 2012 - Wiley Online Library
Nonsense‐mediated mRNA decay (NMD) is a highly conserved pathway that was originally
identified as a RNA surveillance mechanism that degrades aberrant mRNAs harboring …