Recent advances in epitranscriptomics have unveiled functional associations between RNA
modifications (RMs) and multiple human diseases, but distinguishing the functional or …

Deciphering the biological impacts of millions of single nucleotide variants remains a major
challenge. Recent studies suggest that RNA modifications play versatile roles in essential …

Distinguishing the few disease-related variants from a massive number of passenger
variants is a major challenge. Variants affecting RNA modifications that play critical roles in …

More than 100 distinct chemical modifications to RNA have been characterized so far.
However, the prevalence, mechanisms and functions of various RNA modifications remain …

RNA modifications have recently emerged as a widespread and complex facet of gene
expression regulation. Counting more than 170 distinct chemical modifications with far …

In the past few years, thorough investigation of chemical modifications operated in the cells
on ribonucleic acid (RNA) molecules is gaining momentum. This new field of research has …

Innovations in epitranscriptomics have resulted in the identification of more than 160 RNA
modifications to date. These developments, together with the recent discovery of writers …

Although over 170 chemical modifications have been identified, their prevalence,
mechanism and function remain largely unknown. To enable integrated analysis of diverse …

RNA modification is a dynamic and reversible process regulated by a series of writers,
erasers and readers (WERs). Abnormal changes of WERs will disrupt the RNA modification …

With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …