Neuropathic pain following peripheral nerve injury is associated with hyperexcitability in
damaged myelinated sensory axons, which begins to normalise over time. We investigated …

Neuropathic pain following peripheral nerve injury is associated with hyperexcitability in
damaged myelinated sensory axons, which begins to normalise over time. We investigated …

Neuropathic pain (NP) embraces a broad range of conditions linked with a disease or lesion
of the peripheral or central somatosensory system and its prevalence in the general …

Neuropathic pain (NP) embraces a broad range of conditions linked with a disease or lesion
of the peripheral or central somatosensory system and its prevalence in the general …

Peripheral nerve injuries caused by trauma are associated with increased sensory neuron
excitability and debilitating chronic pain symptoms. Axotomy-induced alterations in the …

Saltatory conduction in myelinated fibres depends on a specific molecular organization of
axonal domains: the nodal, paranodal and juxtaparanodal regions. During development …

Chronic neuropathic pain affects millions of individuals worldwide, is typically long-lasting,
and remains poorly treated with existing therapies. Neuropathic pain arising from peripheral …

Neuropathic pain is a severe health problem for which there is a lack of effective therapy. A
frequent underlying condition of neuropathic pain is a sustained overexcitability of pain …

Voltage-gated potassium channels (KV) regulate pain transmission by controlling neuronal
excitability. Changes in KV expression patterns may thus contribute toward hyperalgesia …

Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder characterized
by myokymia and attacks of ataxic gait precipitated by stress events. Several genetic …