Critical limb ischemia (CLI) is a severe form of peripheral arterial disease (PAD) marked by
ischemic rest pain, tissue loss, or gangrene. CLI is associated with significant morbidity …

Critical limb ischemia (CLI) remains a significant cause of morbidity and mortality in patients
with peripheral arterial disease. Optimal treatment strategies for CLI remain controversial …

Critical limb ischemia (CLI) is the most severe form of peripheral arterial disease and is
associated with a risk of limb loss. This vascular condition is currently treated with limb …

Background For patients with critical limb ischemia (CLI), the optimal treatment to enhance
limb preservation, prevent death, and improve functional status is unknown. We performed a …

Data on efficacy outcomes of endovascular versus surgical revascularization in patients with
critical limb ischemia (CLI) in contemporary practice are limited. In this prospective cohort …

Background Critical limb ischemia (CLI) is increasing in prevalence, and remains a
significant source of mortality and limb loss. The decision to recommend surgical or …

Opinion statement Critical limb ischemia (CLI), defined as chronic ischemic rest pain, ulcers,
or gangrene attributable to objectively proven arterial occlusive disease, is the most …

Opinion statement Critical limb ischemia (CLI) is the most severe manifestation of peripheral
artery disease (PAD). Without timely recognition, appropriate diagnosis, and …

Objective Critical limb ischemia is associated with a significant morbidity and mortality. We
systematically reviewed the evidence to compare bypass surgery with endovascular …

Lower extremity critical limb ischemia (CLI) represents symptoms related to end-stage
atherosclerotic peripheral arterial disease manifested by rest pain and tissue loss. It is …