The potential of B7-H6 as a therapeutic target in cancer immunotherapy
Immune checkpoints are vital molecules that regulate T-cell function by activation or
inhibition. Among the immune checkpoint molecules, the B7-family proteins are significantly …
inhibition. Among the immune checkpoint molecules, the B7-family proteins are significantly …
[HTML][HTML] B7-H7: A potential target for cancer immunotherapy
Q Su, J Du, X Xiong, X Xie, L Wang - International Immunopharmacology, 2023 - Elsevier
Cancer immunotherapy enhances the body's immunity against tumors by mitigating immune
escape. Compared with traditional chemotherapy, immunotherapy has the advantages of …
escape. Compared with traditional chemotherapy, immunotherapy has the advantages of …
The B7 family member B7-H6: a new bane of tumor
Y Chen, J Mo, X Jia, Y He - Pathology & Oncology Research, 2018 - Springer
B7-H6 is a ligand of NKp30, which is an activating receptor of natural killer (NK) cells. High
expression of B7-H6 is found in certain types of tumor cells, such as lymphoma, leukemia …
expression of B7-H6 is found in certain types of tumor cells, such as lymphoma, leukemia …
Could B7-H4 serve as a target to activate anti-cancer immunity?
L Wang, X Heng, Y Lu, Z Cai, Q Yi, F Che - International …, 2016 - Elsevier
It has been over 13 years since the identification of B7-H4, the co-stimulatory molecule of B7
family members. While B7-H4 mRNA is widely distributed protein expression seems to be …
family members. While B7-H4 mRNA is widely distributed protein expression seems to be …
B7-H3 in tumors: friend or foe for tumor immunity?
G Li, Y Quan, F Che, L Wang - Cancer chemotherapy and pharmacology, 2018 - Springer
B7-H3 is a type I transmembrane co-stimulatory molecule of the B7 family. B7-H3 mRNA is
widely distributed in most tissues; however, B7-H3 protein is not constitutively expressed …
widely distributed in most tissues; however, B7-H3 protein is not constitutively expressed …
[HTML][HTML] B7-H6 expression correlates with cancer progression and patient's survival in human ovarian cancer
Y Zhou, Y Xu, L Chen, B Xu, C Wu… - International journal of …, 2015 - ncbi.nlm.nih.gov
Abstract B7-H6, a newly identified B7 family member molecule, binds to its receptor on NK
cells, NKp30, and then triggers the anti-tumor NK cell cytotoxicity and leads to the cytokine …
cells, NKp30, and then triggers the anti-tumor NK cell cytotoxicity and leads to the cytokine …
[HTML][HTML] B7-H3, a checkpoint molecule, as a target for cancer immunotherapy
S Yang, W Wei, Q Zhao - International journal of biological …, 2020 - ncbi.nlm.nih.gov
Abstract B7-H3 (also known as CD276) is a newly found molecule of B7 family, which may
be a promising target for cancer treatment. B7-H3 protein was demonstrated to be …
be a promising target for cancer treatment. B7-H3 protein was demonstrated to be …
B7-H1 pathway and its role in the evasion of tumor immunity
B7-H1 is a recently identified member of the B7 family molecules. Upon ligation to its
receptors on T cells it regulates activation and differentiation of T cells. B7-H1 preferentially …
receptors on T cells it regulates activation and differentiation of T cells. B7-H1 preferentially …
[HTML][HTML] Expression of B7-H6 expression in human hepatocellular carcinoma and its clinical significance
L Chen, J Feng, B Xu, Y Zhou, X Zheng, C Wu… - Cancer cell …, 2018 - Springer
Background Recent studies have suggested that B7-H6, a new member of the B7 family of
ligands, not only is a crucial regulator of NK cell-mediated immune responses but also has …
ligands, not only is a crucial regulator of NK cell-mediated immune responses but also has …
Expression of costimulatory molecule B7-H4 in human malignant tumors
Abstract Costimulatory molecule B7-H4, a member of the B7 family, negatively regulates the
immune response of T cells through inhibiting their proliferation, cytokine production and cell …
immune response of T cells through inhibiting their proliferation, cytokine production and cell …