Spatial extent of a single lipid's influence on bilayer mechanics

KC Sapp, AH Beaven, AJ Sodt - Physical Review E, 2021 - APS
To what spatial extent does a single lipid affect the mechanical properties of the membrane
that surrounds it? The lipid composition of a membrane determines its mechanical …

Mechanical properties of lipid bilayers: a note on the Poisson ratio

MM Terzi, M Deserno, JF Nagle - Soft matter, 2019 - pubs.rsc.org
We investigate the Poisson ratio ν of fluid lipid bilayers, ie, the question how area strains
compare to the changes in membrane thickness (or, equivalently, volume) that accompany …

Softening in two-component lipid mixtures by spontaneous curvature variance

A Hossein, AH Beaven, K Sapp… - The Journal of Physical …, 2023 - ACS Publications
The bending modulus of a lipid bilayer quantifies its mechanical resistance to curvature. It is
typically understood in terms of thickness; eg, thicker bilayers are usually stiffer. Here, we …

Additional contributions to elastic energy of lipid membranes: Tilt-curvature coupling and curvature gradient

KV Pinigin, PI Kuzmin, SA Akimov, TR Galimzyanov - Physical Review E, 2020 - APS
Lipid bilayer membranes under biologically relevant conditions are flexible thin laterally fluid
films consisting of two unimolecular layers (monolayers) each about 2 nm thick. On spatial …

[HTML][HTML] Determining the pivotal plane of fluid lipid membranes in simulations

X Wang, M Deserno - The Journal of chemical physics, 2015 - pubs.aip.org
Each leaflet of a curved lipid membrane contains a surface at which the area strain
vanishes, the so-called pivotal plane. Its distance z 0 from the bilayer's midplane arises in …

Curvature and Lipid Packing Modulate the Elastic Properties of Lipid Assemblies: Comparing HII and Lamellar Phases

N Johner, D Harries, G Khelashvili - The journal of physical …, 2014 - ACS Publications
Accumulating evidence indicates that membrane reshaping and fusion processes, as well
as regulation of membrane protein function, depend on lipid composition. Although it is …

Scaling relationships for the elastic moduli and viscosity of mixed lipid membranes

EG Kelley, PD Butler, R Ashkar… - Proceedings of the …, 2020 - National Acad Sciences
The elastic and viscous properties of biological membranes play a vital role in controlling
cell functions that require local reorganization of the membrane components as well as …

Determining the Gaussian curvature modulus of lipid membranes in simulations

M Hu, JJ Briguglio, M Deserno - Biophysical journal, 2012 - cell.com
The Gaussian curvature modulus κ¯ of lipid bilayers likely contributes more than 100
kcal/mol to every cellular fission or fusion event. This huge impact on membrane remodeling …

Molecular mechanisms of spontaneous curvature and softening in complex lipid bilayer mixtures

HJ Lessen, KC Sapp, AH Beaven, R Ashkar, AJ Sodt - Biophysical Journal, 2022 - cell.com
Membrane reshaping is an essential biological process. The chemical composition of lipid
membranes determines their mechanical properties and thus the energetics of their shape …

[HTML][HTML] A consistent quadratic curvature-tilt theory for fluid lipid membranes

MM Terzi, MF Ergüder, M Deserno - The Journal of chemical physics, 2019 - pubs.aip.org
The tilt of a lipid molecule describes the deviation of its orientation away from the local
normal of its embedding membrane. Tilt is the subleading degree of freedom after a …