Refining antimicrobial photodynamic therapy: effect of charge distribution and central metal ion in fluorinated porphyrins on effective control of planktonic and biofilm …

B Pucelik, A Barzowska, A Sułek, M Werłos… - Photochemical & …, 2024 - Springer
Antibiotic resistance represents a pressing global health challenge, now acknowledged as a
critical concern within the framework of One Health. Photodynamic inactivation of …

Photoinactivation of bacterial and fungal planktonic/biofilm forms using the combination of a porphyrinic formulation with potassium iodide

C Vieira, M Bartolomeu, AR Santos… - Medical Sciences …, 2022 - mdpi.com
Antimicrobial photodynamic therapy (aPDT) is a promising approach against multidrug-
resistant microorganisms. In this work, we accessed the photodynamic efficiency of an …

[HTML][HTML] Advances on antimicrobial photodynamic inactivation mediated by Zn (II) porphyrins

THS Souza, JF Sarmento-Neto, SO Souza… - … of Photochemistry and …, 2021 - Elsevier
Over the years, microorganisms have developed several resistance mechanisms against
standard treatments, thus limiting the effect of drugs and rendering ineffective therapies …

Photoinactivation of Pseudomonas aeruginosa Biofilm by Dicationic Diaryl-Porphyrin

VT Orlandi, E Martegani, F Bolognese… - International Journal of …, 2021 - mdpi.com
In recent years, antimicrobial photodynamic therapy (aPDT) has received increasing
attention as a promising tool aimed at both treating microbial infections and sanitizing …

Pyrazole-pyridinium porphyrins and chlorins as powerful photosensitizers for photoinactivation of planktonic and biofilm forms of E. coli

I Santos, SRD Gamelas, C Vieira, MAF Faustino… - Dyes and …, 2021 - Elsevier
In nature, microorganisms can form highly structured complexes designed as biofilms, that
cause severe and chronic infectious in humans. The formation of biofilms provides microbes …

Advances in efficacy enhancement of photosensitizer-mediated photodynamic antimicrobial chemotherapy

BM Isaiah, EK Amuhaya, CI Muhanji - Journal of Porphyrins and …, 2023 - World Scientific
The fight against pathogenic microorganisms has in recent decades been met with fierce
setbacks owing to the antimicrobial resistance phenomenon. Conventional antimicrobials …

Alkylated EDTA potentiates antibacterial photodynamic activity of protoporphyrin

Y Piao, S Himbert, Z Li, J Liu, Z Zhao, H Yu… - Journal of …, 2024 - Springer
Antibiotic resistance has garnered significant attention due to the scarcity of new antibiotics
in development. Protoporphyrin IX (PpIX)-mediated photodynamic therapy shows promise …

Bactericidal efficiency of porphyrin systems

B Habermeyer, T Chilingaryan… - Journal of Porphyrins and …, 2021 - World Scientific
Photodynamic Inactivation is an innovative technique used to combat bacterial and viral
infections which involves the use of photosensitizing agents along with light to generate …

Important cellular targets for antimicrobial photodynamic therapy

MM Awad, A Tovmasyan, JD Craik… - Applied microbiology …, 2016 - Springer
The persistent problem of antibiotic resistance has created a strong demand for new
methods for therapy and disinfection. Photodynamic inactivation (PDI) of microbes has …

Potassium iodide potentiates broad-spectrum antimicrobial photodynamic inactivation using photofrin

L Huang, G Szewczyk, T Sarna… - ACS infectious …, 2017 - ACS Publications
It is known that noncationic porphyrins such as Photofrin (PF) are effective in mediating
antimicrobial photodynamic inactivation (aPDI) of Gram-positive bacteria or fungi. However …