Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 …

G Shishodia, G Verma, Y Srivastava, R Mehrotra… - BMC cancer, 2014 - Springer
Background Aberrantly expressed and constitutively active STAT3 signaling plays a pivotal
role in initiation and progression of human papillomavirus-induced cervical carcinogenesis …

Alterations in microRNAs miR-21 and let-7a correlate with aberrant STAT3 signaling and downstream effects during cervical carcinogenesis

G Shishodia, S Shukla, Y Srivastava, S Masaldan… - Molecular cancer, 2015 - Springer
Background Present study provides clinical evidence of existence of a functional loop
involving miR-21 and let-7a as potential regulators of aberrant STAT3 signaling recently …

The STAT3‐miR‐223‐TGFBR3/HMGCS1 axis modulates the progression of cervical carcinoma

J Zhang, M Jiang, L Qian, X Lin, W Song… - Molecular …, 2020 - Wiley Online Library
Cervical cancer is induced by persistent infections with high‐risk human papillomaviruses
(HPVs), which produce the early protein 6 of HPVs (E6)/E7 protein that is involved in cell …

[HTML][HTML] MicroRNA-27b up-regulated by human papillomavirus 16 E7 promotes proliferation and suppresses apoptosis by targeting polo-like kinase2 in cervical …

F Liu, S Zhang, Z Zhao, X Mao, J Huang, Z Wu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The infection with high-risk human papillomavirus is linked to cervical cancer, nevertheless,
the role of miRNAs regulated by HPV oncogenes in cancer progression remain largely …

Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6

X Wang, HK Wang, JP McCoy, NS Banerjee, JS Rader… - Rna, 2009 - rnajournal.cshlp.org
MicroRNAs (miRNA) play pivotal roles in controlling cell proliferation and differentiation.
Aberrant miRNA expression in human is becoming recognized as a new molecular …

miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway

CON Leung, W Deng, TM Ye, HYS Ngan… - …, 2014 - academic.oup.com
Human papillomaviruses (HPVs) is the principal etiological agent of cervical cancer (CC).
However, exposure to the high-risk type HPV alone is insufficient for tumor formation, and …

miR-2861 acts as a tumor suppressor via targeting EGFR/AKT2/CCND1 pathway in cervical cancer induced by human papillomavirus virus 16 E6

J Xu, X Wan, X Chen, Y Fang, X Cheng, X Xie, W Lu - Scientific reports, 2016 - nature.com
Persistent infection with oncogenic human papillomavirus viruses (HPVs) is a casual factor
for cervical cancer and its precursors and the abnormal constitutive expression of viral …

[HTML][HTML] Human papillomavirus type 16 E6 suppresses microRNA-23b expression in human cervical cancer cells through DNA methylation of the host gene C9orf3

CLA Yeung, TY Tsang, PL Yau, TT Kwok - Oncotarget, 2017 - ncbi.nlm.nih.gov
Oncogenic protein E6 of human papillomavirus type 16 (HPV-16) is believed to involve in
the aberrant methylation in cervical cancer as it upregulates DNA methyltransferase 1 …

The expression of miR-21 and miR-143 is deregulated by the HPV16 E7 oncoprotein and 17β-estradiol

Y Gomez-Gomez… - International …, 2016 - spandidos-publications.com
MicroRNAs (miRNAs) are a class of non-coding RNAs that negatively regulate their target
mRNAs at a posttranscriptional level, thereby affecting crucial processes in cancer …

The high-risk HPV oncogene E7 upregulates miR-182 expression through the TGF-β/Smad pathway in cervical cancer

J Chen, Y Deng, L Ao, Y Song, Y Xu, CC Wang… - Cancer letters, 2019 - Elsevier
Accumulating experimental evidence has shown that the aberrant expression of microRNAs
(miRNAs) is involved in the development and progression of human cervical cancer …