Ziprasidone malate, a new trimorphic salt with improved aqueous solubility
A Portell, R Barbas, M Font-Bardia, P Dalmases… - …, 2009 - pubs.rsc.org
A new salt of ziprasidone with high aqueous solubility has been discovered as a result of a
salt screening and it has been found to exist in three anhydrous polymorphic forms. One of …
salt screening and it has been found to exist in three anhydrous polymorphic forms. One of …
The improvement of the dissolution rate of ziprasidone free base from solid oral formulations
D Zakowiecki, K Cal, K Kaminski, K Adrjanowicz… - AAPS …, 2015 - Springer
This work aims at increasing solubility and dissolution rate of ziprasidone free base—
Biopharmaceutics Classifaction System (BCS) class II compound. The authors describe a …
Biopharmaceutics Classifaction System (BCS) class II compound. The authors describe a …
Improved ziprasidone formulations with enhanced bioavailability in the fasted state and a reduced food effect
AG Thombre, SM Herbig, JA Alderman - Pharmaceutical research, 2011 - Springer
Purpose To develop and characterize new formulations of ziprasidone with a reduced food
effect achieved by increasing exposure in the fasted state. Methods Formulations were …
effect achieved by increasing exposure in the fasted state. Methods Formulations were …
Development and validation of an HPLC method for determination of ziprasidone and its impurities in pharmaceutical dosage forms
M Pavlovic, M Malesevic, K Nikolic… - Journal of AOAC …, 2011 - academic.oup.com
Ziprasidone is known as a novel “atypical” or “second-generation” antipsychotic drug. A
sensitive and reproducible method was developed and validated for determination of …
sensitive and reproducible method was developed and validated for determination of …
[PDF][PDF] Development of rapid and robust stability-indicating method for analysis of ziprasidone (hydrochloride and freebase) as drug substance and in medicines by …
D Zakowiecki, K Cal - Acta Pol Pharm, 2012 - ppm-system.gumed.edu.pl
Ultra Performance Liquid Chromatography (UPLC) was employed to develop a rapid and
robust method for the analysis of ziprasidone, both as a drug substance and in the final …
robust method for the analysis of ziprasidone, both as a drug substance and in the final …
A rapid stability-indicating LC method for ziprasidone hydrochloride
A Singh, BM Rao, GR Deshpande, S Sangaraju… - Chromatographia, 2007 - Springer
A simple and rapid reversed-phase liquid chromatographic method was developed for the
related substances determination and quantitative evaluation of ziprasidone hydrochloride …
related substances determination and quantitative evaluation of ziprasidone hydrochloride …
[HTML][HTML] A new simple and rapid validated RP-HPLC method for determination of ziprasidone in ziprasidone capsules
R Bansal, K Chandrabose, NSHN Moorthy… - Journal of Saudi …, 2016 - Elsevier
In this work, a new isocratic reverse phase chromatographic method was developed using
HPLC for ziprasidone hydrochloride monohydrate (ZHM). The newly developed method is …
HPLC for ziprasidone hydrochloride monohydrate (ZHM). The newly developed method is …
Stability indicating reversed‐phase high‐performance liquid chromatographic and thin layer densitometric methods for the determination of ziprasidone in bulk …
ZA El‐Sherif, B El‐Zeany… - Biomedical …, 2004 - Wiley Online Library
Two sensitive and reproducible methods were developed and validated for the
determination of ziprasidone (ZIP) in the presence of its degradation products in pure form …
determination of ziprasidone (ZIP) in the presence of its degradation products in pure form …
Estimation of ziprasidone hydrochloride monohydrate in bulk and capsules by reverse phase HPLC
BS Rani, PV Reddy - Journal of Chemistry, 2006 - Wiley Online Library
A reverse phase HPLC method is described for the determination of Ziprasidone HCl mono
hydrate in bulk and pharmaceutical dosage forms. Chromatography was carried out on an …
hydrate in bulk and pharmaceutical dosage forms. Chromatography was carried out on an …
[PDF][PDF] Enhancing dissolution rate of ziprasidone via co-grinding technique with highly hydrophilic carriers
JS Patil, AV Korachagaon, SS Shiralashetti… - RGUHS J Pharm …, 2012 - researchgate.net
Ziprasidone belongs to the class II biopharmaceutical classification system (BCS) which is
characterized by a low aqueous solubility, slow dissolution and high membrane …
characterized by a low aqueous solubility, slow dissolution and high membrane …