A new salt of ziprasidone with high aqueous solubility has been discovered as a result of a
salt screening and it has been found to exist in three anhydrous polymorphic forms. One of …

This work aims at increasing solubility and dissolution rate of ziprasidone free base—
Biopharmaceutics Classifaction System (BCS) class II compound. The authors describe a …

Purpose To develop and characterize new formulations of ziprasidone with a reduced food
effect achieved by increasing exposure in the fasted state. Methods Formulations were …

Ziprasidone is known as a novel “atypical” or “second-generation” antipsychotic drug. A
sensitive and reproducible method was developed and validated for determination of …

Ultra Performance Liquid Chromatography (UPLC) was employed to develop a rapid and
robust method for the analysis of ziprasidone, both as a drug substance and in the final …

A simple and rapid reversed-phase liquid chromatographic method was developed for the
related substances determination and quantitative evaluation of ziprasidone hydrochloride …

In this work, a new isocratic reverse phase chromatographic method was developed using
HPLC for ziprasidone hydrochloride monohydrate (ZHM). The newly developed method is …

Two sensitive and reproducible methods were developed and validated for the
determination of ziprasidone (ZIP) in the presence of its degradation products in pure form …

A reverse phase HPLC method is described for the determination of Ziprasidone HCl mono
hydrate in bulk and pharmaceutical dosage forms. Chromatography was carried out on an …

Ziprasidone belongs to the class II biopharmaceutical classification system (BCS) which is
characterized by a low aqueous solubility, slow dissolution and high membrane …