Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data
Background: Hyperglycemia is associated with increased mortality in critically ill patients.
Randomized trials of intensive insulin therapy have reported inconsistent effects on mortality …
Randomized trials of intensive insulin therapy have reported inconsistent effects on mortality …
Insulin therapy for critically ill hospitalized patients: a meta-analysis of randomized controlled trials
Background Hyperglycemia is common in critically ill hospitalized patients, and it is
associated with adverse outcomes, including increased mortality. The objective of this meta …
associated with adverse outcomes, including increased mortality. The objective of this meta …
Insulin therapy and in‐hospital mortality in critically ill patients: systematic review and meta‐analysis of randomized controlled trials
Background: Hyperglycemia is common in critically ill hospitalized patients and has been
associated with adverse outcomes, including increased mortality. In this review, we examine …
associated with adverse outcomes, including increased mortality. In this review, we examine …
Intensive versus conventional insulin therapy: a randomized controlled trial in medical and surgical critically ill patients
Objective: The role of intensive insulin therapy in medical surgical intensive care patients
remains unclear. The objective of this study was to examine the effect of intensive insulin …
remains unclear. The objective of this study was to examine the effect of intensive insulin …
Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm
G Van den Berghe, A Wilmer, I Milants, PJ Wouters… - Diabetes, 2006 - Am Diabetes Assoc
Intensive insulin therapy (IIT) improves the outcome of prolonged critically ill patients, but
concerns remain regarding potential harm and the optimal blood glucose level. These …
concerns remain regarding potential harm and the optimal blood glucose level. These …
Hypoglycemia with intensive insulin therapy in critically ill patients: predisposing factors and association with mortality
Objectives: To examine the predisposing factors for hypoglycemia in medical-surgical
intensive care unit patients treated with intensive insulin therapy and to assess its …
intensive care unit patients treated with intensive insulin therapy and to assess its …
Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis
PE Marik, JC Preiser - Chest, 2010 - Elsevier
Background Following publication of the Leuven Intensive Insulin Therapy Trial in 2001,
tight glycemic control became the standard of care in ICUs around the world. Recent studies …
tight glycemic control became the standard of care in ICUs around the world. Recent studies …
Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target?
G Van den Berghe, M Schetz… - The Journal of …, 2009 - academic.oup.com
Context: Hyper-and hypoglycemia are associated with increased mortality of critically ill
patients, but whether this association is causal remains unclear. Early randomized …
patients, but whether this association is causal remains unclear. Early randomized …
Intensive insulin therapy for critically III patients
KS Lewis, SL Kane-Gill, MB Bobek… - Annals of …, 2004 - journals.sagepub.com
OBJECTIVE: To evaluate the clinical outcomes of glycemic control of intensive insulin
therapy and recommend its place in the management of critically ill patients. DATA …
therapy and recommend its place in the management of critically ill patients. DATA …
Intensive insulin therapy in hospitalized patients: a systematic review
D Kansagara, R Fu, M Freeman, F Wolf… - Annals of internal …, 2011 - acpjournals.org
Background: The benefits and harms of intensive insulin therapy (IIT) titrated to strict
glycemic targets in hospitalized patients remain uncertain. Purpose: To evaluate the benefits …
glycemic targets in hospitalized patients remain uncertain. Purpose: To evaluate the benefits …