Alzheimer's disease is a multifactorial, progressive, age-related neurodegenerative disease.
In familial Alzheimer's disease, Aβ is excessively produced and deposited because of …

In Alzheimer's disease (AD), oxidative stress is present early and contributes to disease
pathogenesis. We previously reported that in Tg19959 transgenic AD mice, partial …

A growing body of evidence suggests a relationship between oxidative stress and β‐amyloid
(Aβ) peptide accumulation, a hallmark in the pathogenesis of Alzheimer's disease (AD) …

Amyloid beta protein (Aβ) in Alzheimer's disease induces oxidative stress through several
mechanisms, including stimulation of nitric oxide synthase (NOS) activity. We examined …

Cognitive impairment in Alzheimer's disease (AD) is strongly associated with both extensive
deposition of amyloid β peptides and oxidative stress, but the exact role of these indices in …

Expression of manganese superoxide dismutase (MnSOD), a nuclear-encoded
mitochondrial primary antioxidant enzyme, is protective against various paradigms of …

Alzheimer's disease (AD) is associated with β-amyloid accumulation, oxidative stress and
mitochondrial dysfunction. However, the effects of genetic mutation of AD on oxidative status …

Background Alzheimer's disease (AD) is a progressive neurodegenerative disease,
characterized by severe cognitive impairment. Hallmark pathological changes include senile …

Numerous studies have demonstrated oxidative damage in the central nervous system in
subjects with Alzheimer disease and in animal models of this dementing disorder. In this …