Objective: Evidences from cell culture experiments suggest a link between cholesterol and
nervous system disease. Statins may have neurotoxic or neuroprotective effects, but these …

Statins are potent inhibitors of the hydroxy‐methyl‐glutaryl‐coenzyme A reductase, the rate
limiting enzyme for cholesterol biosynthesis. Experimental and clinical studies with statins …

Background: Statins represent a class of medications widely prescribed to efficiently treat
dyslipidemia. These drugs inhibit 3-βhydroxy 3β-methylglutaryl Coenzyme A reductase …

Statins have been widely used for the treatment of a variety of conditions beyond their
original role in lowering cholesterol. Since statins have relatively few side effects, they have …

Statins have, at present, the potential to provide a new therapeutic target for various
neurological diseases. It is well established that statins reduce cholesterol levels and …

Statins are currently among the most commonly prescribed agents for the prevention of
cardiovascular disease. Statins reduce serum cholesterol levels by reversibly inhibiting 3 …

Statins are inhibitors of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase, an enzyme
necessary for the production of mevalonate. They are widely used as cholesterol-lowering …

Statins are commonly prescribed lipid-lowering medications that significantly reduce the risk
of cardiovascular events. In addition to their ability to lower cholesterol by affecting the rate …

Statins with a closed‐ring structure (mevastatin, lovastatin, and simvastatin) and with an
open‐ring structure (pravastatin and fluvastatin) are widely used in the human population to …

Background Statins are lipid-lowering drugs widely used in the world. They are effective and
safe in the treatment and in the primary and secondary prevention of cerebrovascular and …