Multi‐band echo‐planar spectroscopic imaging of hyperpolarized 13C probes in a compact preclinical PET/MR scanner
C von Morze, T Blazey, R Baeza… - Magnetic resonance …, 2022 - Wiley Online Library
Purpose Hyperpolarized (HP) 13C MRI has enabled real‐time imaging of specific enzyme‐
catalyzed metabolic reactions, but advanced pulse sequences are necessary to capture the …
catalyzed metabolic reactions, but advanced pulse sequences are necessary to capture the …
Development of a symmetric echo planar imaging framework for clinical translation of rapid dynamic hyperpolarized 13C imaging
JW Gordon, DB Vigneron… - Magnetic resonance in …, 2017 - Wiley Online Library
Purpose To develop symmetric echo planar imaging (EPI) and a reference scan framework
for hyperpolarized 13C metabolic imaging. Methods Symmetric, ramp‐sampled EPI with …
for hyperpolarized 13C metabolic imaging. Methods Symmetric, ramp‐sampled EPI with …
A vendor‐neutral EPI sequence for hyperpolarized 13C MRI
T Blazey, A Shaw, C von Morze - Magnetic resonance in …, 2024 - Wiley Online Library
Purpose To develop a flexible, vendor‐neutral EPI sequence for hyperpolarized 13C
metabolic imaging. Methods An open‐source EPI sequence consisting of a metabolite …
metabolic imaging. Methods An open‐source EPI sequence consisting of a metabolite …
Fast dynamic 3D MR spectroscopic imaging with compressed sensing and multiband excitation pulses for hyperpolarized 13C studies
Hyperpolarized 13C MR spectroscopic imaging can detect not only the uptake of the pre‐
polarized molecule but also its metabolic products in vivo, thus providing a powerful new …
polarized molecule but also its metabolic products in vivo, thus providing a powerful new …
Metabolite-Specific Echo-Planar Imaging of Hyperpolarized [1-13C]Pyruvate at 4.7 T
Although hyperpolarization (HP) greatly increases the sensitivity of 13C MR, the usefulness
of HP in vivo is limited by the short lifetime of HP agents. To address this limitation, we …
of HP in vivo is limited by the short lifetime of HP agents. To address this limitation, we …
Imaging considerations for in vivo 13C metabolic mapping using hyperpolarized 13C‐pyruvate
One of the challenges of optimizing signal‐to‐noise ratio (SNR) and image quality in 13C
metabolic imaging using hyperpolarized 13C‐pyruvate is associated with the different MR …
metabolic imaging using hyperpolarized 13C‐pyruvate is associated with the different MR …
Radial spectroscopic MRI of hyperpolarized [1‐13C] pyruvate at 7 tesla
MS Ramirez, J Lee, CM Walker… - Magnetic resonance …, 2014 - Wiley Online Library
Purpose The transient and nonrenewable signal from hyperpolarized metabolites
necessitates extensive sequence optimization for encoding spatial, spectral, and dynamic …
necessitates extensive sequence optimization for encoding spatial, spectral, and dynamic …
Chemical shift separation with controlled aliasing for hyperpolarized 13C metabolic imaging
PJ Shin, PEZ Larson, M Uecker… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose A chemical shift separation technique for hyperpolarized 13C metabolic imaging
with high spatial and temporal resolution was developed. Specifically, a fast three …
with high spatial and temporal resolution was developed. Specifically, a fast three …
Comparison of selective excitation and multi-echo chemical shift encoding for imaging of hyperpolarized [1-13C] pyruvate
Imaging methods for hyperpolarized (HP) 13 C agents must sample the evolution of signal
from multiple agents with distinct chemical shifts within a very brief timeframe (typically< 1 …
from multiple agents with distinct chemical shifts within a very brief timeframe (typically< 1 …
In vivo single-shot 13C spectroscopic imaging of hyperpolarized metabolites by spatiotemporal encoding
Hyperpolarized metabolic imaging is a growing field that has provided a new tool for
analyzing metabolism, particularly in cancer. Given the short life times of the hyperpolarized …
analyzing metabolism, particularly in cancer. Given the short life times of the hyperpolarized …